Intervertebral spinal implant

ABSTRACT

An intervertebral implant for implantation in an intervertebral space between vertebrae. The implant includes a body extending from an upper surface to a lower surface. The body has a front end, a rear end and a pair of spaced apart first and second side walls extending between the front and rear walls such that an internal chamber is defined within the front and rear ends and the first and second walls. The body defines an outer perimeter and an inner perimeter extending about the internal chamber. At least one of the side walls is defined by an integral porous structure.

CROSS REFERENCE TO RELATED APPLICATION

This application is a continuation of U.S. patent application Ser. No.16/921,986, which is a continuation of U.S. patent application Ser. No.16/238,136, filed Jan. 2, 2019, which is a continuation-in-part of U.S.patent application Ser. No. 16/151,737, filed Oct. 4, 2018, which is acontinuation-in-part of U.S. patent application Ser. No. 15/973,818,filed May 8, 2018, which are incorporated by reference herein in theirentireties for all purposes. This patent application is also related toU.S. patent application Ser. No. 15/973,609 filed May 8, 2018; U.S.patent application Ser. No. 15/973,756 filed May 8, 2018; U.S. patentapplication Ser. No. 15/973,772 filed May 8, 2018; U.S. patentapplication Ser. No. 15/973,788 filed May 8, 2018; U.S. patentapplication Ser. No. 15/973,801 filed May 8, 2018; and U.S. patentapplication Ser. No. 15/973,831 filed May 2018, which are allincorporated by reference herein in their entireties for all purposes.

FIELD

The present disclosure generally relates to fixation devices and systemsfor positioning and immobilizing at least two adjacent vertebrae andmethods related to the same. In particular, the present disclosurerelates to interbody fusion devices with an integrated solid supportstructure and porous ingrowth structure.

BACKGROUND

The spine is the axis of the skeleton on which all of the body parts“hang”. In humans, the normal spine has seven cervical, twelve thoracicand five lumbar segments. The lumbar spine situs upon the sacrum, whichthen attaches to the pelvis, and in turn is supported by the hip and legbones. The bony vertebral bodies of the spine are separated byintervertebral discs, which act as joints but allow known degrees offlexion, extension, lateral bending, and axial rotation.

The typical vertebra has a thick anterior bone mass called the vertebralbody, with a neural (vertebral) arch that arises from the posteriorsurface of the vertebral body. The central of adjacent vertebrae aresupported by intervertebral discs. The spinal disc and/or vertebralbodies may be displaced or damaged due to trauma, disease, degenerativedefects, or wear over an extended period of time. One result of thisdisplacement or damage to a spinal disc or vertebral body may be chronicback pain. In many cases, to alleviate back pain from degenerated ofherniated discs, the disc is removed along with all or part of at leastone neighboring vertebrae and is replaced by an implant that promotesfusion of the remaining bony anatomy.

However, the success or failure of spinal fusion may depend upon severalfactors. For instance, the spacer or implant or cage used to fill thespace left by the removed disc and bony anatomy must be sufficientlystrong to support the spine under a wide range of loading conditions.The spacer should also be configured so that it likely to remain inplace once it has been positioned in the spine by the surgeon.Additionally, the material used for the spacer should be biocompatiblematerial and should have a configuration that promotes bony ingrowth.

SUMMARY

To meet this and other needs, intervertebral implants for use with theanterior, antero-lateral, lateral, and/or posterior portions of at leastone motion segment unit of the spine, systems, and methods are provided.Traditionally, interbody spacers or implants intended to help facilitateintervertebral fusion may serve as a means to restore intervertebralheight and/or lordosis. The implant may feature a central lumen to housebone graft material. It is through this central lumen where most of thefusion may occur. The implants of the disclosure incorporate avolumetric, interconnected porosity throughout the entire spacer. Thisenables bone to grow into and/or through the spacer, making it part ofthe fusion mass. The incorporation of a volumetric, interconnectedporosity within the implant may encourage faster, strongerintervertebral fusion.

According to one embodiment, an intervertebral implant for implantationin an intervertebral space between vertebrae is disclosed. The implantincludes a body extending from an upper surface to a lower surface. Thebody has a front end, a rear end and a pair of spaced apart first andsecond side walls extending between the front and rear walls such thatan interior chamber is defined within the front and rear ends and thefirst and second walls. The body defines an outer perimeter and an innerperimeter extending about the internal chamber. At least one of the sidewalls is defined by an integral porous structure which extends from theouter perimeter to the inner perimeter. The at least one of the sidewalls is free of vertical solid support structure between the upper andlower surface.

According to another embodiment, an intervertebral implant forimplantation in an intervertebral space between vertebrae is provided.The implant includes a body having a front end, a rear end and opposedside walls extending between the ends. The body has an outer perimeterand an inner perimeter about an internal chamber. The includes an uppersurface and a lower surface with the upper surface defined by a solidupper outer rim and a spaced apart solid upper inner rim and the lowersurface defined by a solid lower outer rim and a spaced apart solidlower inner rim. A solid front wall extends at the front end between atleast the solid upper outer rim and the solid lower outer rim. A solidrear wall extends at the rear end between at least the solid upper outerrim and the solid lower outer rim. Each of the side walls is free of anysolid struts extending between the upper and lower surfaces. A porousstructure is integrally formed with the solid upper rims, the solidlower rims, and the solid front and rear walls and extends from the bodyouter perimeter to the body inner perimeter.

According to another embodiment, a method of forming an intervertebralimplant for implantation in an intervertebral space between vertebrae isprovided. The method includes forming an upper surface defined by asolid upper outer rim and a spaced apart solid upper inner rim; forminga lower surface defined by a solid lower outer rim and a spaced apartsolid lower inner rim; forming a solid front wall extending at a frontend between at least the solid upper outer rim and the solid lower outerrim; forming a solid rear wall extending at a rear end between at leastthe solid upper outer rim and the solid lower outer rim; forming sidewalls extending between the front and rear ends with each of the sidewalls free of any solid struts extending between the upper and lowersurfaces; and forming a porous structure integral with the solid upperrims, the solid lower rims and the solid front and rear walls, theporous structure extending from an outer perimeter of the implant to aninner perimeter extending about an internal chamber of the implant.

BRIEF DESCRIPTION OF THE DRAWINGS

A more complete understanding of the present disclosure, and theattendant advantages and features thereof, will be more readilyunderstood by reference to the following detailed description whenconsidered in conjunction with the accompanying drawings wherein:

FIGS. 1-4 are perspective, side, top and rear views, respectively, of anintervertebral implant according to one embodiment of the disclosurewith the porous portions shown textured;

FIGS. 5-7 are perspective, top and side views, respectively, of theintervertebral implant of FIGS. 1-4 with the porous portions removed toshow the support structure;

FIGS. 8-10 are perspective, top and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown translucently;

FIGS. 11-13 are perspective, top and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown translucently;

FIGS. 14-16 are perspective, top and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown translucently;

FIGS. 17-19 are perspective, top and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown translucently;

FIGS. 20-22 and 24 are perspective, top, side and rear views,respectively, of an intervertebral implant according to anotherembodiment of the disclosure with the porous portions shown textured,and FIG. 23 is a cross-sectional view along the lines 23-23 in FIG. 21 ;

FIGS. 25-27 are perspective, top and side views, respectively, of theintervertebral implant of FIGS. 20-24 with the porous portions removedto show the support structure;

FIGS. 28-31 are perspective, top, side and rear views, respectively, ofan intervertebral implant according to another embodiment of thedisclosure with the porous portions shown textured;

FIGS. 32-34 are perspective, top and side views, respectively, of theintervertebral implant of FIGS. 28-31 with the porous portions removedto show the support structure;

FIGS. 35 and 36 are perspective and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown translucently;

FIGS. 37 and 38 are rear and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown translucently;

FIG. 39 is a perspective view of an intervertebral implant according toanother embodiment of the disclosure with the porous portions showntranslucently;

FIGS. 40-43 are perspective, top, side and rear views, respectively, ofan intervertebral implant according to another embodiment of thedisclosure with the porous portions shown textured;

FIGS. 44-47 are perspective, top, side and rear views, respectively, ofthe intervertebral implant of FIGS. 40-43 with the porous portionsremoved to show the support structure;

FIGS. 48-51 are perspective, top, side and rear views, respectively, ofan intervertebral implant according to another embodiment of thedisclosure with the porous portions shown translucently;

FIGS. 52 and 53 are perspective and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown translucently;

FIGS. 54-57 are perspective, rear, top and side views, respectively, ofan intervertebral implant according to another embodiment of thedisclosure with the porous portions shown translucently;

FIGS. 58-61 are perspective, top, side and rear views, respectively, ofan intervertebral implant according to another embodiment of thedisclosure with the porous portions shown textured;

FIGS. 62-64 are perspective, top and side views, respectively, of theintervertebral implant of FIGS. 58-61 with the porous portions removedto show the support structure;

FIGS. 65-67 are perspective, top and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown translucently;

FIGS. 68 and 69 are perspective and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown translucently;

FIGS. 70-72 are perspective, top and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown translucently;

FIGS. 73-75 are perspective, top and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown translucently;

FIGS. 76 and 77 are perspective and top views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown textured;

FIGS. 78 and 79 are perspective and top views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown textured;

FIGS. 80-83 are front perspective, rear perspective, top and side views,respectively, of the spacer portion of the implants of FIGS. 76-79 withthe porous portions shown textured;

FIGS. 84-86 are perspective, top and side views, respectively, of thespacer portion of FIGS. 80-83 with the porous portions removed to showthe support structure;

FIGS. 87 and 88 are illustrative photos of various porous structures inaccordance with embodiments of the disclosure;

FIGS. 89-92 are perspective, bottom, side and rear views, respectively,of an intervertebral implant according to another embodiment of thedisclosure with the porous portions shown textured;

FIGS. 93-96 are perspective, bottom, side and rear views, respectively,of the intervertebral implant of FIGS. 89-92 with the porous portionsremoved to show the support structure;

FIGS. 97 and 98 are top and side views, respectively, of anintervertebral implant according to another embodiment of the disclosureand FIG. 99 is a cross-sectional view along the line 99-99 in FIG. 97 ;

FIGS. 100 and 101 are side views of an intervertebral implant accordingto another embodiment of the disclosure, with FIG. 101 illustrating aninsertion tool extending through the implant;

FIG. 102 is a perspective view of an intervertebral implant according toanother embodiment of the disclosure, FIG. 103 is a cross-sectional viewalong the line 103-103 in FIG. 102 and FIG. 104 is a cross-sectionalview along the line 104-104 in FIG. 102 ;

FIGS. 105 and 106 are front and perspective views, respectively,illustrating a grid porous configuration;

FIG. 107 is a perspective view of an intervertebral implant according toanother embodiment of the disclosure;

FIG. 108 is a perspective view of an intervertebral implant according toanother embodiment of the disclosure;

FIG. 109 is a side view of an intervertebral implant according toanother embodiment of the disclosure;

FIGS. 110-112 are perspective, side and top views, respectively, of anintervertebral implant according to another embodiment of the disclosureand FIG. 113 is a cross-sectional view along the line 113-113 in FIG.112 ;

FIGS. 114 and 115 illustrate alternative strut patterns of anillustrative support structure;

FIG. 116 is a perspective view of an intervertebral implant according toanother embodiment of the disclosure;

FIG. 117 is a cross-sectional view of an intervertebral implantaccording to another embodiment of the disclosure;

FIG. 118 is a top view of an intervertebral implant according to anotherembodiment of the disclosure and FIG. 119 is a cross-sectional viewalong the line 119-119 in FIG. 118 ;

FIGS. 120 and 121 are top and rear views, respectively, of anintervertebral implant according to another embodiment of the disclosureand FIG. 122 is a cross-sectional view along the line 122-122 in FIG.121 ;

FIG. 123 is a side view of an intervertebral implant according toanother embodiment of the disclosure;

FIGS. 124 and 125 are top and side views, respectively, of anintervertebral implant according to another embodiment of the disclosureand FIG. 126 is a cross-sectional view along the line 126-126 in FIG.124 ;

FIG. 127 is a side view of an intervertebral implant according toanother embodiment of the disclosure and FIG. 128 is a cross-sectionalview along the line 128-128 in FIG. 127 ;

FIG. 129 is an exploded side view of an intervertebral implant accordingto another embodiment of the disclosure;

FIGS. 130-132 are top views showing sequentially implantation of anexpandable intervertebral implant according to another embodiment of thedisclosure;

FIGS. 133 and 134 are front and top views, respectively, of anintervertebral implant according to another embodiment of the disclosureand FIG. 135 is a cross-sectional view along the line 135-135 in FIG.134 ;

FIG. 136 is a perspective view illustrating an example tool hole andFIG. 137 is a cross-sectional view illustrating a toll engaged in such ahole;

FIG. 138 is a schematic view of an example delivery tool in accordancewith an embodiment of the disclosure;

FIGS. 139-141 are perspective, top and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown textured;

FIGS. 142 and 143 are perspective and top views, respectively, of theintervertebral implant of FIGS. 139-141 with the porous portions removedto show the support structure;

FIGS. 144 and 145 are perspective and top views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions shown textured;

FIGS. 146 and 147 are perspective and top views, respectively, of theintervertebral implant of FIGS. 144 and 145 with the porous portionsremoved to show the support structure;

FIGS. 148-150 are perspective, top and side views, respectively, of anintervertebral implant according to another embodiment of the disclosurewith the porous portions removed to show the support structure;

FIGS. 151-153 are left perspective, right perspective and side views,respectively, of an intervertebral implant according to anotherembodiment of the disclosure with the porous portions shown textured;

FIGS. 154-156 are perspective, top and side views, respectively, of theintervertebral implant of FIGS. 151-153 with the porous portions removedto show the support structure;

FIGS. 157-160 are perspective, top, side and rear views, respectively,of an intervertebral implant according to another embodiment of thedisclosure with the porous portions shown textured;

FIGS. 161-163 are perspective, top and side views, respectively, of theintervertebral implant of FIGS. 157-160 with the porous portions removedto show the support structure;

FIGS. 164-166 are perspective top and side views, respectively, ofanother embodiment of a spacer portion of the implants of FIGS. 76-79with the porous portions shown textured;

FIGS. 167-169 are perspective, top and side views, respectively, of thespacer portion of FIGS. 164-166 with the porous portions removed to showthe support structure;

FIGS. 170-172 are perspective, top and side views, respectively, of astandalone interbody spacer according to another embodiment;

FIGS. 173-176 are perspective and top views, and perspective and topviews without the porous portions of a spacer according to anotherembodiment;

FIGS. 177-180 are perspective and top views, and perspective and topviews with the porous portions of a spacer according to anotherembodiment;

FIGS. 181-182 are side views with and without the porous portionsaccording to another embodiment;

FIGS. 183-188 are perspective, side and top views with and withoutporous portions according to another embodiment;

FIGS. 189-192 are rear and perspective views of the implant of FIG. 183with and without the porous portions present;

FIGS. 193-198 are perspective, top and side views with and without theporous portions present for an implant according to another embodiment;and

FIGS. 199-203 are perspective, cross-section, and top and close up viewsof a corpectomy implant according to another embodiment.

DETAILED DESCRIPTION

Embodiments of the disclosure are generally directed to intervertebralimplants, systems, and method of use thereof. The implant may besuitable for use with the anterior, antero-lateral, lateral, and/orposterior portions of at least one motion segment unit of the spine.Traditionally, interbody spacers or implants intended to help facilitateintervertebral fusion may serve as a means to restore intervertebralheight and/or lordosis. The implants may feature a central lumen tohouse bone graft material, for example. It is through this central lumenwhere most of the fusion may occur. The implants of the disclosure mayincorporate a volumetric, interconnected porosity throughout the entirespacer or a portion thereof. This enables bone to growth into and/orthrough the spacer or a portion thereof, making it part of the fusionmass. The incorporation of a volumetric, interconnected porosity mayencourage faster, stronger intervertebral fusion, thereby providing forbetter patient outcomes.

Various forms of additive manufacturing, or 3D printing, have beendeveloped which allow structures to be formed layer by layer. Oneillustrative 3D printing technology is Direct Metal Laser Sintering(DMLS) wherein parts are built using a laser to selectively sinter (heatand fuse) a powdered metal material into layers. The process begins oncea 3D CAD file is mathematically sliced into multiple 2D cross sectionsand uploaded into the system. After the first layer is produced, thebuild platform is lowered, another powder layer is spread across theplate, and the laser sinters the second layer. This process is repeateduntil the part is complete. Layer-by-layer manufacturing allows for thedirect fabrication of complex parts that would be cost-prohibitive, andoften impossible, to produce through traditional manufacturingprocesses. The powder layer thickness used during the fabrication of thespacers may be as thin at 30 μm. The resolution of the laser may be asfine as 70 μm. Although it is envisioned that any suitable thickness orlaser resolution may be used or selected.

The disclosure is not limited to DMLS, but various 3D printing methodsmay be utilized. For example, VAT Photopolymerization utilizes a vat ofliquid photopolymer resin which is cured through selective exposure tolight (via a laser or projector) which then initiates polymerization andconverts the exposed areas to a solid part. As another example, PowderBed Fusion, of which DMLS is a subcategory, utilizes powdered materialswhich are selectively consolidated by melting it together using a heatsource such as a laser or electron beam. The powder surrounding theconsolidated part acts as support material for overhanging features.

As yet another example, in Binder Jetting Liquid bonding agents areselectively applied onto thin layers of powdered material to build upparts layer by layer. The binders include organic and inorganicmaterials. Metal or ceramic powdered parts are typically fired in afurnace after they are printed. Material Jetting is another example of a3D printing process which may be utilized wherein droplets of materialare deposited layer by layer to make parts. Common varieties includejetting a photocurable resin and curing it with UV light, as well asjetting thermally molten materials that then solidify in ambienttemperatures. As another example, in Sheet Lamination sheets of materialare stacked and laminated together to form an object. The laminationmethod can be adhesives or chemical (paper/plastics), ultrasonicwelding, or brazing (metals). Unneeded regions are cut out layer bylayer and removed after the object is built. Another example of a 3Dprinting process that may be utilized is Material Extrusion whereinmaterial is extruded through a nozzle or orifice in tracks or beads,which are then combined into multi-layer models. Common varietiesinclude heated thermoplastic extrusion and syringe dispensing. Yetanother example is Directed Energy Deposition wherein powder or wire isfed into a melt pool which has been generated on the surface of the partwhere it adheres to the underlying part or layers by using an energysource such as a laser or electron beam.

The implants of the disclosure may be manufactured from any of these orother additive manufacturing processes currently known or laterdeveloped. The implants may also be manufactured utilizing a combinationof additive manufacturing processes and other manufacturing processes,for example, laser etching. Additionally, the implants may be furtherprocessed during and/or after manufacture utilizing various techniques,for example, abrasion, machining, polishing, or chemical treatment. Theimplants may be manufactured from various materials, such asbiocompatible materials, including metals, polymers, ceramics orcombinations thereof. Exemplary materials include Titanium (and Titaniumalloys), Cobalt-Chrome, PEEK, and/or Stainless Steel, for example.

As will be discussed in more detail hereinafter, the implants of thedisclosure generally comprise a solid support structure and a porousstructure formed integral therewith. The solid support structure mayinclude solid front and rear walls interconnected by upper and lowerimplant surfaces. The upper and lower surfaces may include spaced apartrims with cross struts interconnecting the rims. In many embodiments,the solid support structure of the upper and lower surfaces includes aplurality of openings in which the integral porous structure is formedsuch that the porous structure extends along at least a portion of theupper and lower implant surfaces. The side walls extending between thefront and rear walls generally have a minimal solid structure, forexample, a plurality of struts extending between the upper and lowerrims, but otherwise have open area therebetween in which the integralporous structure is formed. The configuration of the solid structure isselected to provide the implant sufficient structural integrity andmechanical stability while maximizing the area of porous structure whichfacilitates better integration/incorporation with the adjacent bone. Inseveral embodiments of the disclosure, the solid structure generallyencases the corners of the porous structure or otherwise houses theporous structure therein to maintain the structural integrity of theporous structure.

Referring now to FIGS. 1-7 , one embodiment of a cervical intervertebralimplant 10 will be described. As illustrated, the implant 10 has a body11 with a generally trapezoidal shape. The body 11 is defined by atapered front end 12, a rectangular rear end 14 and side walls 16 and 18extending therebetween. The implant 10 has an outer perimeter OPextending about the body 11. A hollow interior chamber 13 is definedwithin an inner perimeter IP of the body 11. The hollow interior chamber13 is configured to receive bone growth promoting materials, forexample. The implant 10 has an upper surface 20 and a lower surface 22,with both surfaces having a tapering portion 23 at the front end 12. Theupper and lower surfaces 20, 22 may be substantially parallel orotherwise configured to provide the proper intervertebral spacing. Theupper and lower surfaces 20, 22 define a plurality of serrations 24along the side walls 16, 18 and a plurality of serrations 26 along therear end 14. The serrations 24, 26 are defined by both the solid supportstructure 30 and the porous structure 50. As will be described in detailhereinafter, the solid support structure 30 includes spaced apart rims32, 34 and 36, 38 with cross struts 31 and 37. The solid supportstructure 30 defines open spaces or recesses adjacent the cross struts31, 37 and the porous structure 50 is formed within such open spacessuch that the solid structure 30 and the porous structure 50 togetherform the serrations 24, 26. As illustrated in FIGS. 1-4 , the porousstructure 50 extends to and forms a portion of the implant upper andlower surfaces 20-22. The rear end 14 of the implant 10 includes a hole25 and a pair of blind slots 27 for receiving an instrument that is usedfor inserting the implant 10. As seen in FIGS. 1-4 , the implant 10 isdefined by a solid support structure 30 with an interfiled, integralporous structure 50.

The solid support structure 30 will be described in more detail withreference to FIGS. 5-7 . An outer rim 32 extends about the outerperimeter OP of the upper surface 20 and an inner rim 34 extends aboutthe inner perimeter IP of the upper surface 20, i.e. about the interiorchamber 13. Similarly, an outer rim 36 extends about the outer perimeterOP of the lower surface 22 and an inner rim 38 extends about the innerperimeter IP of the lower surface 22. A plurality of cross struts 31extend between the outer rims 32, 36 and the respective inner rims 34,38 along the side wall areas. As seen in the figures, the cross struts31 along with contoured portions 33 of the rims 32, 34, 36, 38 definethe contour of the serrations 24. In addition to interconnecting therims within a given upper or lower surface, struts 44, 46 and 48 extendwithin each side wall area to interconnect the upper rims 32, 34 withthe lower rims 36, 38. In the illustrated embodiment, a first strut 44extends from the lower inner rim 38 to the upper outer rim 32 near therear portion of the support structure 30, a second strut 46 extends fromthe lower inner rim 38 to the upper outer rim 32 near the front portionof the support structure 30 and an X-shaped strut 48 extends betweenboth lower rims 36, 38 and both upper rims 32, 34 at a central locationof the support structure 30. As can be seen in FIGS. 6 and 7 , each ofthe first struts 44 extends from the lower inner rim 38 proximate therear wall 35 at an angle to approximately the midpoint of the upperouter rim 32, substantially tangent to the curvature of the inner rims34, 38. Similarly, each of the second struts 46 extends from the lowerinner rim 38 proximate the front wall 40 at an angle to approximatelythe midpoint of the upper outer rim 32, substantially tangent to thecurvature of the inner rims 34, 38. Each of the X-shaped struts 48extends substantially parallel to the upper and lower rims andpositioned at the point where the first and second struts 44, 46 meetwith the upper outer rim 36. The struts may have other configurationsand more or fewer struts may be utilized.

The solid rear wall 35 additionally interconnects the outer rims 32, 36and the respective inner rims 34, 38 along the rear end area as well asfurther connecting the upper and lower structures together. The solidrear wall 35 defines the hole 25 and slots 27. Recessed areas 39 and 41on the upper and lower sides of the rear wall 35 define receiving areasfor porous structure, as seen in FIGS. 1-4 . Cross members 37 in thisarea along with contours of the outer rims 32, 36 define the serrations26. The solid front wall 40 has a concave configuration and alsointerconnects the outer rims 32, 36 and the respective inner rims 34, 38along the front end area. The front wall 40 includes an upper slopedportion 42 extending between the upper outer rim 32 and inner rim 34 anda lower sloped portion 43 extending between the lower outer rim 36 andinner rim 38. While the rims and walls are described as specificelements for clarity, it is understood that the elements are formed as aunitary structure and may be formed as a smooth structure without anydistinction between the elements.

In the illustrations of the support structure 30 shown in FIGS. 5-7 withthe porosity omitted for illustration, it is seen that there issignificant open space between the upper rims 32, 34 and the lower rims36, 38 with only the struts 44, 46, 48 therebetween. The struts 44, 46,48 occupy only a minimal space between the upper and lower rims 32, 34,36, 38, for example, less than 50% of the wall space, thereby leavingsubstantial open space for the porous structure 50. Additionally, thereis open space between the inside surface of the front wall 40 and theinner rims 34, 38. Furthermore, there is open space on an inside surfaceand the recesses 39, 41 of the rear wall 35. As illustrated in FIGS. 1-4, in the implant 10, these open spaces are filled with the porousstructure 50 such that the porous structure 50 encapsulates the struts44, 46, 48 and extends from the upper surface 20 to the lower surface 22and from the outer perimeter OP to the inner perimeter IP. In theillustrated embodiment, the porous structure 50 substantially definesthe inner perimeter IP and defines a substantial portion of the sidewalls 16, 18 along the outer perimeter OP.

The configuration of the support structure 30 and the porous structure50 are selected, for example, to provide the implant with an adequateconstruct strength while maximizing the potential for bony in-growth andallowing for clear radiographic imaging. Referring to FIGS. 87 and 88 ,the porous structure 50 may have a randomized pattern of open pores 50 aor a repeating pattern of open pores 50 b. The porous structure 50 mayhave a suitable porosity (open volume). For example, the porousstructure 50 may be greater than 50% open, greater than 60% open,greater than 70% open, or approximately 70% open, or approximately 75%open. The porous structure 50 may feature interconnected pores or openpores. The porous structure 50 may have pores, for example, ranging fromapproximately 100 μm-2 mm, approximately 100 μm-1 mm, approximately200-900 μm, or approximately 300-800 μm in diameter. The pore size mayhave an average pore size of about 300-800 μm, about 400-700 μm, orabout 500-600 μm. The pore size distribution may be unimodal orbi-modal. Although spherical or partially-spherical pores or nodes areexemplified in forming the porous structure, it is envisioned that othersuitable pore shapes and configurations may be used, for example,repeating or random patterns of cylinders, cubes, cones, pyramids,polyhedrons, or the like.

It is contemplated that different areas of the support structure 30 mayhave varying stiffness or strength, for example, variable A-P stiffnessto achieve optimized load on an anterior graft or to achieve a desiredlevel of flexibility within the implant 10. Furthermore, the porousstructure 50 may have different porosities or densities in differentareas of the implant 10. For example, the porous structure 50 may have ahigher porosity or density along the inner perimeter compared to that atthe outer perimeter, for example, with the inner area having acancellous porosity and the outer area having a cortical porosity. Theporous structure 50 may have various configurations, for example, a gridor honeycomb pattern which may promote bony in-growth. Additionally, theporous structure 50 may be configured such that when it is turned past acritical angle it may appear opaque, thereby helping with assessment ofthe implant orientation or positioning. The surface texture of both thesupport structure and the porous structure may be controlled to provideboth macro and micro texturizing. The features and characteristicsdescribed with respect to this embodiment may be incorporated in any ofthe embodiments described herein. Additionally, features described inany of the embodiments herein may be incorporated into any of the otherembodiments.

Referring now to FIGS. 8-10 , a cervical intervertebral implant 10′ inaccordance with another embodiment of the disclosure will be described.The implant 10′ is similar to the previous embodiment except for aslight modification in the structure of the support structure 30′ and acorresponding modification in the porous structure 50′. Compared to theprevious embodiment, the rear wall 35′ has a narrower width with aportion of the rear end 14′ having an open support structure into whichthe porous structure 50′ extends. With the narrower width, the recessedportions 39′, 41′ open directly into the open space of the side walls16′, 18′ and rear end 14′. To maintain sufficient implant strength, apair of X-shaped struts 48′, 48″ are positioned in each of the side wallareas 16′, 18′ proximate the rear end 14′ of the implant 10′. While thefront end 12 of the implant 10′ remains substantially the same as in theprevious embodiment, an additional X-shaped strut 48′″ is p positionedin each of the side wall areas 16′, 18′ proximate the rear end 14′ ofthe implant 10′. Again, in the implant 10′, the open spaces are filledwith the porous structure 50′ such that the porous structure 50′encapsulates the struts 44, 46, 48, 48′, 48″, 48′″ and extends from theupper surface 20 to the lower surface 22 and from the outer perimeter OPto the inner perimeter IP. In the illustrated embodiment, the porousstructure 50′ substantially defines the inner perimeter IP and defines asubstantial portion of the side walls 16′, 18′ and a portion of the rearend 14′ along the outer perimeter OP.

Referring now to FIGS. 11-13 , a cervical intervertebral implant 10″ inaccordance with another embodiment of the disclosure will be described.The implant 10″ is similar to the previous embodiment except for slightmodification in the structure of the support structure 30″ and acorresponding modification in the porous structure 50″. In the presentembodiment, the struts within the side walls are replaced with externalX-shaped struts 60, 62. Outer X-shaped struts 60 extend along each ofthe side walls 16″, 18″ along the outer perimeter OP. The outer X-shapedstruts 60 extend between the upper and lower outer rims 32 and 36. InnerX-shaped struts 62 extend along each of the side walls 16″, 18″ alongthe inner perimeter IP. The inner X-shaped struts 62 extend between theupper and lower inner rims 34 and 38. A generally hollow wall space isdefined between the outer and inner X-shaped struts 60, 62 on the sidesand the cross struts 31, 37 on the top and bottom. These hollow wallspaces extend from the front wall 40 to the rear wall 35′ and are filledwith the integral porous structure 50″. Again, in the implant 10″, theopen spaces are filled with the porous structure 50″ such that itextends from the upper surface 20 to the lower surface 22 and from theouter perimeter OP to the inner perimeter IP. In the present embodiment,the struts 60, 62 are not encapsulated in the porous structure 50″, butinstead the struts 60 are coplanar with the porous structure 50″ alongthe outer perimeter OP and the struts 62 are coplanar with the porousstructure 50″ along the inner perimeter IP. Again, the porous structure50″ substantially defines the inner perimeter IP and defines asubstantial portion of the side walls 16″, 18″ and a portion of the rearend 14′ along the outer perimeter OP.

Referring now to FIGS. 14-16 , a cervical intervertebral implant 10′″ inaccordance with another embodiment of the disclosure will be described.The implant 10′″ is similar to the previous embodiment except for slightmodification in the structure of the support structure 30′″ and acorresponding modification in the porous structure 50′″. In the presentembodiment, the external X-shaped struts 60′, 62′ have a narrowerconfiguration and have curved portions compared to those of the previousembodiment. Again, outer X-shaped struts 60′ extend along each of theside walls 16″, 18″ along the outer perimeter OP as they extend betweenthe upper and lower outer rims 32 and 36. Inner X-shaped struts 62′extend along each of the side walls 16″, 18″ along the inner perimeterIP as they extend between the upper and lower inner rims 34 and 38. Inthe present embodiment, in the rear area 14″ of the implant 10′″, therear wall 35″ is not connected to the upper or lower rim 32, 36 andinstead open spaces 61 extend therebetween. As in the previousembodiment, a generally hollow wall space is defined between the outerand inner X-shaped struts 60′, 62′ on the sides and the cross struts 31,37 on the top and bottom. These hollow wall spaces extend from the frontwall 40 to the rear wall 35″ and are filled with the integral porousstructure 50′″. As in the previous embodiments, all of the open spacesof the implant 10′″ are filled with the porous structure 50′″ such thatit extends from the upper surface 20 to the lower surface 22 and fromthe outer perimeter OP to the inner perimeter IP. As in the previousembodiment, the struts 60′, 62′ are not encapsulated in the porousstructure 50′″, but instead the struts 60′ are coplanar with the porousstructure 50′″ along the outer perimeter OP and the struts 62′ arecoplanar with the porous structure 50′″ along the inner perimeter IP.Again, the porous structure 50′″ substantially defines the innerperimeter IP and defines a substantial portion of the side walls 16″,18″ and a portion of the rear end 14″ along the outer perimeter OP.

Referring now to FIGS. 17-19 , a cervical intervertebral implant 10′ inaccordance with another embodiment of the disclosure will be described.The implant 10″ is similar to the previous embodiment except for slightmodification in the structure of the support structure 30′° and acorresponding modification in the porous structure 50 ^(iv). In thepresent embodiment, the struts are replaced with an internal corrugatedwall 64 within each of the side walls 16′″, 18′″. Each corrugated wall64 extends between the upper support structure and the lower supportstructure. In the illustrated embodiment, each corrugated wall 64extends from the front wall 12, interconnects with the cross struts 31,37 and interconnects with the rear wall 35′″. In the present embodiment,in the rear area 14″ of the implant 10″, open spaces 61 extend betweenthe rear wall 35′″ and the upper or lower rims 32, 36 as in the previousembodiment, however, additional supports 63 extend between the upperrims 32, 34 and the rear wall 35′″ and between the lower rims 36, 38 andthe rear wall 35′″. As in the previous embodiments, all of the openspaces of the implant 10 ^(iv) are filled with the porous structure 50^(iv) such that it extends from the upper surface 20 to the lowersurface 22. The porous structure 50 ^(iv) of the present embodimentencapsulates each corrugated wall 64 and while the porous structure 50^(iv) is not continuous from the outer perimeter OP to the innerperimeter IP, the porous structure 50 ^(iv) still substantially definesthe inner perimeter IP and defines a substantial portion of the sidewalls 16″, 18″ and a portion of the rear end 14″ along the outerperimeter OP.

Referring now to FIGS. 148-150 , a cervical intervertebral implant 10^(v) in accordance with another embodiment of the disclosure will bedescribed. The implant 10 ^(v) is similar to the embodiment illustratedin FIGS. 1-7 except for slight modification in the structure of thesupport structure 30 ^(v) and a corresponding modification in the porousstructure. In the present embodiment, the support structure 30 ^(v) isfree of any struts within the side walls 16 ^(iv), 18 ^(iv). Instead,the upper outer rim 32 is interconnected to the lower outer rim 36 viathe front and rear walls 40, 35 and the inner rims 34, 38 are connectedto the respective outer rims 32, 36 via the cross struts 31. As in theprevious embodiments, all of the open spaces of the implant 10 ^(v) arefilled with the porous structure such that it extends from the uppersurface 20 to the lower surface 22. The implant 10 ^(v) of the presentembodiment looks substantially the same as the implant 10 of FIGS. 1-4and the porous structure substantially defines the inner perimeter IPand defines a substantial portion of the side walls 16 ^(iv), 18 ^(iv)and a portion of the rear end 14 along the outer perimeter OP.

Turning now to FIGS. 193-198 , a cervical intervertebral implant 10^(vi) in accordance with another embodiment is provided. Implant 10^(vi) is similar to the embodiment illustrated in FIGS. 148-150 exceptthe interior chamber 13 has been filled with porous structure 50. Itwill be appreciated that any of the openings or chambers in anyembodiment may be replaced with the porous structure 50 to promote bonegrowth and healing. In this embodiment, the porous structure 50 fillingprior chamber 13 extends from the upper surface 20 to the lower surface22 of the implant 10 ^(vi). The porous structure 50 within the formerchamber 13 may further define teeth or serrations 26, for example, inline with the serrations 26 on the remainder of the upper and lowersurfaces 20, 22 of the implant. The porous structure 50 may be the sameor different than the remainder of the porous structure 50 elsewhere inthe implant 10 ^(vi).

Referring now to FIGS. 151-156 , a cervical intervertebral implant 10^(vi) in accordance with another embodiment of the disclosure will bedescribed. The implant 10 ^(vi) is similar to the embodiment illustratedin FIGS. 148-150 except for slight modification in the structure of thesupport structure 30 ^(vi) and a corresponding modification in theporous structure. In the present embodiment, a lateral window 70 isdefined through each of the side walls 16 ^(v), 18 ^(v). The lateralwindows 70 may, for example, aid in assessing bony fusion inpost-operative X-ray images. In the present embodiment, each lateralwindow 70 includes a respective solid window frame 71, however, it isunderstood that the lateral windows may be defined in the side walls 16^(v), 18 ^(v) by the porous structure 50 ^(vi) only without any solidframe or the like.

Each of the illustrative solid frames 71 includes an outer frame ring 72and an inner frame ring 74. An intermediate cross strut 76 extendsbetween each outer frame ring 72 and the respective inner frame ring 74.Additionally, an upper front strut 73 extends across the front of thesupport structure 30 ^(vi), interconnecting both the outer rings 72 andinner rings 74 of both solid frames 71. Similarly, a lower front strut75 extends across the front of the support structure 30 ^(vi),interconnecting both the outer rings 72 and inner rings 74 of both solidframes 71. The rear ends of at least the outer rings 72 each connectwith the rear wall 35 to cantileverly support each of the solid frames71.

As in the previous embodiments, all of the open spaces of the implant 10^(vi) are filled with the porous structure 50 ^(vi) such that it extendsfrom the upper surface 20 to the lower surface 22. The porous structure50 ^(vi) substantially defines the inner perimeter IP and defines asubstantial portion of the side walls 16 ^(iv), 18 ^(iv), with thelateral windows 70 extending therethrough.

Referring now to FIGS. 20-27 , one embodiment of an anterior lumbarinterbody fusion (ALIF) implant 110 will be described. As illustrated,the implant 110 has a body 111 with a generally D-shaped configuration.The body 111 is defined by a tapered front end 112, a rectangular rearend 114 and side walls 116 and 118 extending therebetween. The implant110 has an outer perimeter OP extending about the body 111. A hollowinterior chamber 113 is defined within an inner perimeter IP of the body111. The hollow interior chamber 113 is configured to receive bonegrowth promoting materials. The implant 110 has an upper surface 120 anda substantially parallel lower surface 122, with both surfaces having atapering portion 123 at the front end 112. The upper and lower surfaces120, 122 define a plurality of serrations 124 along the side walls 116,118 and a plurality of serrations 126 along the rear end 114. The rearend 114 of the implant 110 includes a plurality of screw holes 125through which screws (not shown) extend to anchor the implant onto thevertebral body. Secondary holes 127 are provided to receive respectiveblocking set screws (not shown). A threaded hole 128 and a blind slot129 are provided for receiving an instrument that is used for insertingthe implant 110. As seen in FIGS. 20-24 , the implant 110 is defined bya solid support structure 130 with an interfiled, integral porousstructure 150.

The solid support structure 130 will be described in more detail withreference to FIGS. 25-25 . An outer rim 132 extends about the outerperimeter OP of the upper surface 120 and an inner rim 134 extends aboutthe inner perimeter IP of the upper surface 120, i.e. about the interiorchamber 113. Similarly, an outer rim 136 extends about the outerperimeter OP of the lower surface 122 and an inner rim 138 extends aboutthe inner perimeter IP of the lower surface 122. A plurality of crossstruts 131 extend between the outer rims 132, 136 and the respectiveinner rims 134, 138 along the side wall areas. As seen in the figures,the cross struts 131 along with contoured portions 133 of the rims 132,134, 136, 138 define the contour of the serrations 124. In addition tointerconnecting the rims within a given upper or lower surface, struts144, 146 extend within each side wall area to interconnect the upperrims 132, 134 with the lower rims 136, 138. In the illustratedembodiment, a first multi-leg strut 144 extends from the lower inner rim138 to the upper outer rim 132 near the rear portion of the supportstructure 130 and a second multi-leg strut 146 extends from the lowerinner rim 138 to the upper outer rim 132 near the front portion of thesupport structure 130.

A solid rear wall 135 additionally interconnects the outer rims 132, 136and the respective inner rims 134, 138 along the rear end area as wellas further connecting the upper and lower structures together. The solidrear wall 135 defines the holes 125, 127, 128 and the slot 129. Recessedareas 139 on the upper and lower sides of the rear wall 135 definereceiving areas for porous structure, as seen in FIGS. 20-24 . Crossmembers 131 in this area along with contours of the outer rims 132, 136define the serrations 126. A solid front wall 140 with a concaveconfiguration also interconnects the outer rims 132, 136 and therespective inner rims 134, 138 along the front end area. The front wall140 includes an upper sloped portion 142 extending between the upperouter rim 132 and inner rim 134 and a lower sloped portion 143 extendingbetween the lower outer rim 136 and inner rim 138. While the rims andwalls are described as specific elements for clarity, it is understoodthat the elements are formed as a unitary structure and may be formed asa smooth structure without any distinction between the elements.

In the illustrations of the support structure 130 in FIGS. 25-27 , it isseen that there is significant open space between the upper rims 132,134 and the lower rims 136, 138 with only the struts 144, 146therebetween. Additionally, there is open space between the insidesurface of the front wall 140 and the inner rims 134, 138. Furthermore,there is open space on an inside surface and the recesses 139, 141 ofthe rear wall 135. As illustrated in FIGS. 20-24 , in the implant 110,these open spaces are filled with the porous structure 150 such that theporous structure 150 encapsulates the struts 144, 146 and extends fromthe upper surface 120 to the lower surface 122 and from the outerperimeter OP to the inner perimeter IP. In the illustrated embodiment,the porous structure 150 substantially defines the inner perimeter IPand defines a substantial portion of the side walls 116, 118 along theouter perimeter OP.

Turning now to FIGS. 170-172 , a standalone ALIF implant 110, similar toimplant 110 shown in FIGS. 20-23 , is provided except that no internalsupport structure exists between the solid support structure 130 at theupper and lower surfaces 120, 122 other than the internal porousstructure 150. As this implant 110 is substantially similar except forthe internal structure, the same reference numbers are provided. Asshown in this embodiment, the solid support structure 130 comprises theouter rim 132 and the inner rim 134 at the upper surface 120, and theouter rim 136 and the inner rim 138 at the lower surface 122. Theplurality of cross struts 131 extend between the respective outer rims132, 136 and the respective inner rims 134, 138. The cross struts 131may include a plurality of substantially parallel struts 131. Theseparallel struts 131 may form the teeth or serrations 124 of the implant110. The parallel struts 131 may be uniformly spaced across the upperand lower surfaces 120, 122 or otherwise configured. The cross struts131 may also include one or more angled struts 131, for example as bestseen in FIG. 171 . These angled struts 131 may be angled relative to theparallel struts 131 in separate quadrants of the upper and lowersurfaces 120, 122. In this embodiment, there are no internal strutsbetween the solid support structure 130 at the upper and lower surfaces120, 122. Instead, the porous structure 150 extends continuously betweenthe solid support structure 130 at the upper and lower surfaces 120,122. The porous structure 150 is also provided in between the struts 131at the upper and lower surfaces 120, 122 to form at least a portion ofthe upper and lower surfaces 120,122 of the implant 110.

Referring now to FIGS. 28-34 , an ALIF implant 110′ in accordance withanother embodiment of the disclosure will be described. The implant 110′is similar to the previous embodiment except for slight modification inthe structure of the support structure 130′ and a correspondingmodification in the porous structure 150′. Compared to the previousembodiment, the upper and lower surfaces 120′, 122′ of the presentimplant 110′ are angled relative to one another. Additionally, the rearwall 135′ has a narrower width with a portion of the rear end 114′having an open support structure into which the porous structure 150′extends. With the narrower width, the recess portions 139′ open directlyinto the open space of the side walls 116′, 118′ and rear end 114′. Therear wall 135′ defines a single opening 128′ for receipt of an insertiontool. A cylinder 145 is positioned between the upper rims 132, 136 andthe lower rims 134, 138 along the rear end 114′. The cylinder 145defines a through bore 147 configured to also receive an insertion tool.To maintain sufficient implant strength in the rear end 114′, a firstX-shaped strut 148 extends between the cylinder 145 and the end wall135′ and a second X-shaped strut 148′ is positioned on the opposite sideof the rear wall 135. The front end 112 of the implant 110′ includes arecessed area 141 which defines a forward serration 149. Again, in theimplant 110′, the open spaces are filled with the porous structure 150′such that the porous structure 150′ encapsulates the struts 144, 146,114, 148′ and extends from the upper surface 120′ to the lower surface122′ and from the outer perimeter OP to the inner perimeter IP. In theillustrated embodiment, the porous structure 150′ substantially definesthe inner perimeter IP and defines a substantial portion of the sidewalls 116′, 118′ and a portion of the rear end 114′ along the outerperimeter OP.

Referring now to FIGS. 35 and 36 , an ALIF implant 110″ in accordancewith another embodiment of the disclosure will be described. The implant110″ is similar to the previous embodiment except for slightmodification in the structure of the support structure 130″ and acorresponding modification in the porous structure 150″. Compared to theprevious embodiment, the rear wall 135″ of the rear end 114″ includes aplurality of slots 129′ positioned about the hole 128′. Additionally,the struts of the previous embodiment are replaced with a plurality ofX-shaped struts 152 which are interconnected to one another by acircumferential intermediate rim 154. Each of the struts 152 alsointerconnects with the upper rims 132, 136 and the lower rims 134, 137.Again, in the implant 110″, the open spaces are filled with the porousstructure 150″ such that the porous structure 150″ encapsulates thestruts 152 and the intermediate rim 154 and extends from the uppersurface 120′ to the lower surface 122′ and from the outer perimeter OPto the inner perimeter IP. In the illustrated embodiment, the porousstructure 150″ substantially defines the inner perimeter IP and definesa substantial portion of the side walls 116′, 118′ and a portion of therear end 114″ along the outer perimeter OP.

Referring now to FIGS. 37 and 38 , an ALIF implant 110′″ in accordancewith another embodiment of the disclosure will be described. The implant110′″ is similar to the previous embodiment except for slightmodification in the structure of the support structure 130″ and acorresponding modification in the porous structure 150″. Compared to theprevious embodiment, the X-shaped struts are replaced by coil struts 156a and 156 b. Coil strut 156 a of side wall area 118′ extends from therear wall 135″ to the front wall 140″ and extends about thecircumferential intermediate rim 154. Similarly, coil strut 156 b ofside wall area 116′ extends from the rear wall 135″ to the front wall140″ and extends about the circumferential intermediate rim 154,however, the cylinder 145 extends through and interconnects with thecoil strut 154 b. Each of the struts 156 a, 156 b also interconnectswith the upper rims 132, 136 and the lower rims 134, 137. Again, in theimplant 110′″, the open spaces are filled with the porous structure150′″ such that the porous structure 150′″ encapsulates the intermediaterim 154 and struts 156 a, 156 b and extends from the upper surface 120′to the lower surface 122′ and from the outer perimeter OP to the innerperimeter IP. In the illustrated embodiment, the porous structure 150′″substantially defines the inner perimeter IP and defines a substantialportion of the side walls 116′, 118′ and a portion of the rear end 114″along the outer perimeter OP.

Referring now to FIG. 39 , an ALIF implant 110 ^(iv) in accordance withanother embodiment of the disclosure will be described. The implant 110^(iv) has a body 111′ with a generally oval configuration. The body 111′is defined by a tapered front end 112″, a rectangular rear end 114′″ andside walls 116″ and 118″ extending therebetween. The implant 110 ^(iv)has an outer perimeter OP extending about the body 111′. A hollowinterior chamber 113 is defined within an inner perimeter IP of the body111′. The hollow interior chamber 113 is configured to receive bonegrowth promoting materials. The implant 110 has an upper surface 120′and a substantially parallel lower surface 122′, with both surfaceshaving a tapering portion 123 at the front end 112. In the presentembodiment, each of the surfaces 120′, 122′ includes a central surfaceportion 175. The upper and lower surfaces 120′, 122′ define a pluralityof serrations 124′ along the side walls 116, 118 and the centralportions 175 and a plurality of serrations 126′ along the rear end114′″. The rear end 114′″ of the implant 110 includes a plurality ofholes 128″, 145 configured for receiving an instrument that is used forinserting the implant 110. As in the previous embodiments, the implant110 ^(iv) is defined by a solid support structure 130 ^(iv) with aninterfiled, integral porous structure 150 ^(iv).

The solid support structure 130 ^(iv) includes an upper plate 160extending from the front end 112″ to the rear end 114′″ and definingside wall portions 162, 164 and central portion 166. A plurality ofrecesses 173 in the upper and lower plates 160, 170 are filled with theporous structure 150 ^(iv) to define the serrations 124′, 126′.Similarly, a lower plate 170 extends from the front end 112″ to the rearend 114′″ and defines side wall portions 172, 174 and central portion176. The upper and lower plates 160, 170 are interconnected by a frontwall 140″ and a rear wall 135″. It is noted that in the presentembodiment, the side walls 116′, 118′ are generally open without anysupport structure and completely filled with the porous structure 150^(iv). The rear wall 135″ defines the holes 128″, 145. The rear wall135″ includes a plurality of recesses 171 configured to receive theporous structure 150 ^(iv). As in the previous embodiments, the porousstructure 150 ^(iv) generally extends from the upper surface 120′ to thelower surface 122′ and from the outer perimeter OP to the innerperimeter IP. In the illustrated embodiment, the porous structure 150^(iv) substantially defines the inner perimeter IP and defines asubstantial portion of the side walls 116′, 118′ along the outerperimeter OP.

Referring now to FIGS. 157-163 , an ALIF implant 110 ^(v) in accordancewith another embodiment of the disclosure will be described. The implant110 ^(v) is similar to the embodiment illustrated in FIGS. 28-34 exceptfor slight modification in the structure of the support structure 130^(v) and a corresponding modification in the porous structure 150 ^(v).The support structure 130 ^(v) of the present embodiment has a tallerconfiguration such that a pair of walls 180 extend between the upperrims 132, 136 and the lower rims 134, 138 along the rear end 114′ tosupport the cylinder 145. Additionally, the rear wall 135′″ includes apair of walls 181, 183 which support the insertion tool opening 128′.The rearward wall 181 is radially inward such that porous structure 150^(v) extends along a substantial portion of the rear end 114′ of theimplant 110 ^(v) as shown in FIG. 160 . To provide additional support inthe rear wall 135′″, an additional angled wall 182 extends between theupper rims 132, 136 and the lower rims 134, 138 on the side of the rearend 114′ opposite the cylinder 145. With this configuration, the rearwall 135′″ provides necessary support but leaves significant open spacefor the porous structure as shown in FIG. 161 .

In the present embodiment, the side walls 116′″, 118′″ are free ofsupport structure between the upper rims 132, 136 and the lower rims134, 138 from the rear wall 135′″ to the front wall 140′″. Foradditional support, an angled wall 184 extends between the upper rims132, 136 and the lower rims 134, 138 at each lateral end of the frontwall 140′″. As such, side wall 116′″ is free of vertical supportstructure between the walls 180 and the angled wall 184 and side wall118′″ is free of vertical support structure between the rear angled wall182 and the front angled wall 184.

Again, in the implant 110 ^(v), the open spaces are filled with theporous structure 150 ^(v) such that the porous structure 150 ^(v)extends from the upper surface 120′ to the lower surface 122′ and fromthe outer perimeter OP to the inner perimeter IP. In the illustratedembodiment, the porous structure 150 ^(v) substantially defines theinner perimeter IP and defines a substantial portion of the side walls116′″, 118′″ and the rear end 114′ along the outer perimeter OP.

Referring now to FIGS. 40-47 , one embodiment of a transforaminal lumbarinterbody fusion (TLIF) implant 210 will be described. As illustrated,the implant 210 has a body 211 with a generally rectangular shape. Thebody 211 is defined by a tapered front end 212, a rectangular rear end214 and side walls 216 and 218 extending therebetween. The implant 210has an outer perimeter OP extending about the body 211. A hollowinterior chamber 213 is defined within an inner perimeter IP of the body211. The hollow interior chamber 213 is configured to receive bonegrowth promoting materials. The implant 210 has an upper surface 220 anda substantially parallel lower surface 222, with both surfaces having atapering portion 223 at the front end 212. The upper and lower surfaces220, 222 define a plurality of serrations 224 between the side walls216, 218 and a plurality of serrations 226 along the rear end 214. Therear end 214 of the implant 210 includes a hole 225 and a pair of slots227 for receiving an instrument that is used for inserting the implant210. The implant 210 is defined by a solid support structure 230 with aninterfiled, integral porous structure 250.

The solid support structure 230 includes an outer rim 232 extendingabout the outer perimeter OP of the upper surface 220 and an inner rim234 extending about the inner perimeter IP of the upper surface 220,i.e. about the interior chamber 213. Similarly, an outer rim 236 extendsabout the outer perimeter OP of the lower surface 222 and an inner rim238 extends about the inner perimeter IP of the lower surface 222. Aplurality of cross struts 231 extend between the outer rims 232, 236 andthe respective inner rims 234, 238 along the side wall areas. As seen inthe figures, the cross struts 231 along with contoured portions 233 ofthe rims 232, 234, 236, 238 define the contour of the serrations 224. Inaddition to interconnecting the rims within a given upper or lowersurface, external radial struts 260, 262 additionally interconnect therims 232, 234, 236, 238. Outer radial struts 260 extend along each ofthe side walls 216, 218 along the outer perimeter OP. The outer radialstruts 260 have a central portion 261 and legs 263 which extend betweenthe upper and lower outer rims 232 and 236. Inner radial struts 262extend along each of the side walls 216, 218 along the inner perimeterIP. The inner radial struts 262 have a central portion 265 and legs 267which extend between the upper and lower inner rims 234 and 238.

A solid rear wall 235 additionally interconnects the outer rims 232, 236and the respective inner rims 234, 238 along the rear end area as wellas further connecting the upper and lower structures together. The solidrear wall 235 defines the hole 225 and slots 227. Recessed areas 239 and241 on the upper and lower sides of the rear wall 235 define receivingareas for porous structure, as seen in FIGS. 40-43 . The contours of theouter rims 232, 236 define the serrations 226. A solid front wall 240with a concave configuration also interconnects the outer rims 232, 236and the respective inner rims 234, 238 along the front end area. Thefront wall 240 includes an upper sloped portion 242 extending betweenthe upper outer rim 232 and inner rim 234 and a lower sloped portion 243extending between the lower outer rim 236 and inner rim 238. While therims and walls are described as specific elements for clarity, it isunderstood that the elements are formed as a unitary structure and maybe formed as a smooth structure without any distinction between theelements.

In the illustrations of the support structure 230 in FIGS. 44-47 , it isseen that there is significant open space between the upper rims 232,234 and the lower rims 236, 238, between the inside surface of the frontwall 240 and the inner rims 234, 238, and on an inside surface and therecesses 239, 241 of the rear wall 235. As illustrated in FIGS. 40-43 ,in the implant 210, the open spaces are filled with the porous structure250 such that it extends from the upper surface 220 to the lower surface222 and from the outer perimeter OP to the inner perimeter IP. In thepresent embodiment, the struts 260, 262 are not encapsulated in theporous structure 250, but instead the struts 260 are coplanar with theporous structure 250 along the outer perimeter OP and the struts 262 arecoplanar with the porous structure 250 along the inner perimeter IP.Again, the porous structure 250 substantially defines the innerperimeter IP and defines a substantial portion of the side walls 216,218 along the outer perimeter OP.

Referring now to FIGS. 48-51 , a TLIF implant 210′ in accordance withanother embodiment of the disclosure will be described. The implant 210′is similar to the previous embodiment except for slight modification inthe structure of the support structure 230′ and a correspondingmodification in the porous structure 250′. In the present embodiment, aconnecting ring 268 interconnects the central portion 261 with thecentral portion 265 of the struts 260, 262 in each side wall 216, 218.Additionally, on the upper and lower surfaces 220, 222, additionalserrations 229 are provided adjacent the rear end 214′. Again, in theimplant 210′, the open spaces are filled with the porous structure 250′such that it extends from the upper surface 220 to the lower surface 222and from the outer perimeter OP to the inner perimeter IP. In thepresent embodiment the struts 260 are coplanar with the porous structure250′ along the outer perimeter OP and the struts 262 are coplanar withthe porous structure 250′ along the inner perimeter IP. The connectingrings 268 are encapsulated within the porous structure 250′. Again, theporous structure 250′ substantially defines the inner perimeter IP anddefines a substantial portion of the side walls 216, 218 along the outerperimeter OP.

Referring now to FIGS. 52 and 53 , a TLIF implant 210″ in accordancewith another embodiment of the disclosure will be described. The implant210″ is similar to the embodiment illustrated in FIGS. 40-47 except forslight modification in the structure of the support structure 230″ and acorresponding modification in the porous structure 250″. In the presentembodiment, in addition to the struts 260, 262, a plurality of X-shapedstruts 244 extend between the upper rims 232, 234 and the lower rims236, 238 in each side wall 216, 218. Again, in the implant 210″, theopen spaces are filled with the porous structure 250″ such that itextends from the upper surface 220 to the lower surface 222 and from theouter perimeter OP to the inner perimeter IP. In the present embodimentthe struts 260 are coplanar with the porous structure 250′ along theouter perimeter OP and the struts 262 are coplanar with the porousstructure 250′ along the inner perimeter IP. The X-shaped struts 244 areencapsulated within the porous structure 250″. Again, the porousstructure 250″ substantially defines the inner perimeter IP and definesa substantial portion of the side walls 216, 218 along the outerperimeter OP.

Referring now to FIGS. 52 and 53 , a TLIF implant 210′″ in accordancewith another embodiment of the disclosure will be described. The implant210′″ is similar to the embodiment illustrated in FIGS. 40-47 except forslight modification in the structure of the support structure 230′″ anda corresponding modification in the porous structure 250′″. In thepresent embodiment, the side walls 216′, 218′ do not include externalstruts, but instead include a plurality of X-shaped struts 246 extendingbetween the upper rims 232, 234 and the lower rims 236, 238 in each sidewall 216′, 218′. Additionally, an intermediate plate 248 interconnectsthe X-shaped struts 246 within each side wall area. Again, in theimplant 210′″, the open spaces are filled with the porous structure250′″ such that the porous structure 250′″ encapsulates the struts 246and the intermediate plate 248 and extends from the upper surface 220 tothe lower surface 222 and from the outer perimeter OP to the innerperimeter IP. In the illustrated embodiment, the porous structure 250′″substantially defines the inner perimeter IP and defines a substantialportion of the side walls 216′, 218′ along the outer perimeter OP.

Turning now to FIGS. 173-176 , a TLIF implant 210 ^(iv), similar toimplants 210, 210′, 210″, and 210′″ shown in FIGS. 44-57 , is providedexcept that no internal support structure exists between the solidsupport structure 230 at the upper and lower surfaces 220, 222 otherthan the internal porous structure 250. As this implant 210 ^(iv) issubstantially similar except for the internal structure, the samereference numbers are provided. FIG. 173 shows a perspective view of theimplant 210 ^(iv) and FIG. 174 shows a perspective view of the solidstructure 230 with the porous portions 250 omitted. Similarly, FIG. 176shows a top view of the implant 210 ^(iv) and FIG. 175 shows a top viewof the solid structure 230 with the porous portions 250 omitted.

As shown in this embodiment, the solid support structure 230 comprisesthe outer rim 232 and the inner rim 234 on the upper surface 220, andthe outer rim 236 and the inner rim 238 on the lower surface 222. Theplurality of cross struts 231 extend between the respective outer rims232, 236 and the respective inner rims 234, 238 and/or between oppositesides of the outer rims 232, 236 near the front and rear ends 212, 214.The cross struts 231 may include a plurality of substantially parallelstruts 231. These parallel struts 231 may form the teeth or serrations224 of the implant 210 ^(iv). The parallel struts 231 may be uniformlyspaced across the upper and lower surfaces 220, 222 or otherwiseconfigured. In this embodiment, there are no internal struts between theupper and lower surfaces 220, 222. Instead, the porous structure 250extends continuously between the solid support structure 230 at theupper and lower surfaces 220, 222. The porous structure 250 is alsoprovided in between the struts 231 at the upper and lower surfaces 220,222 to form at least a portion of the upper and lower surfaces 220,222of the implant 210 ^(iv).

Turning now to FIGS. 177-180 , a TLIF implant 210 ^(v), similar toimplant 210 ^(iv) shown in FIGS. 173-176 , is provided except that oneor more solid walls 237 extend between the solid support structure 230at the upper and lower surfaces 220, 222. As this implant 210 ^(v) issubstantially similar except for the internal structure, the samereference numbers are provided. FIG. 177 shows a perspective view of theimplant 210 ^(v) and FIG. 178 shows a perspective view of the solidstructure 230 with the porous portions 250 omitted. Similarly, FIG. 180shows a top view of the implant 210 ^(v) and FIG. 179 shows a top viewof the solid structure 230 with the porous portions 250 omitted.

As shown in this embodiment, solid walls 237 extend between the solidsupport structure 230 at the upper and lower surfaces 220, 222. Thesolid walls 237 support the cross struts 231 at locations between theouter rim 232 and the inner rim 234 at the upper surface 220 and atlocations between the outer rim 236 and the inner rim 238 at the lowersurface 222. In other words, the solid walls 237 extend continuouslybetween the cross struts 231. The solid walls 237 may be recessed adistance inward from the side walls 216, 218 such that the porousportions 250 cover the inside and outside surfaces of the solid walls237. In this manner, the side walls 216, 218 may be a substantiallyporous structure 250 between the solid support structure 230 at theupper and lower surfaces 220, 222 and the interior chamber 213 may bedefined by a substantially porous structure 250 between the solidsupport structure at the upper and lower surfaces 220, 222. In otherwords, the solid walls 237 may be sandwiched in between the porousportions 250. The solid wall 237 may have a thickness less than athickness of the porous portions 250. The solid walls 237 may extendsubstantially parallel to the side walls 216, 218 and/or substantiallyparallel to the elongated portions of the interior chamber 213. Thesolid walls 237 may also extend substantially perpendicular to the crossstruts 231 or may be otherwise configured to support the cross struts231.

FIGS. 181 and 182 show an alternative version of implant 210 ^(v) wherethe overall height of the implant 210 ^(v) is reduced and the solidwalls 237 and corresponding porous portions 250 cover a smaller surfacearea of the implant 210 ^(v). FIG. 181 shows a side view of the implant210 ^(v) and FIG. 182 shows a side view of the implant 210 ^(v) with theporous portions removed. The dimensions and positioning of the rims 232,234, 236, 238, solid walls 237, and porous portions 250 may be variedbased on the size, shape, and configuration of the implant.

Turning now to FIGS. 183-192 , a TLIF or PLIF implant 210 ^(vi)configured for inserting the implant 210 ^(vi) on its side and rotatingthe implant 210 ^(vi) in situ once the implant 210 ^(vi) is locatedbetween target vertebrae is similar to implant 210 ^(v) shown in FIGS.177-180 . As this implant 210 ^(vi) is substantially similar, the samereference numbers are provided. FIG. 183 shows a perspective view of theimplant 210 ^(vi) and FIG. 184 shows a perspective view of the solidstructure 230 with the porous portions 250 omitted. FIG. 185 shows aside view of the implant 210 ^(vi) and FIG. 186 shows a side view of thesolid structure 230 with the porous portions 250 omitted. FIG. 188 showsa top view of the implant 210 ^(vi) and FIG. 187 shows a top view of thesolid structure 230 with the porous portions 250 omitted. FIG. 190 showsa rear view of the implant 210 ^(vi) and FIG. 189 shows a rear view ofthe solid structure 230 with the porous portions 250 omitted. FIG. 191shows a rear perspective view of the solid structure 230 with the porousportions 250 removed and FIG. 192 shows a partial cross-section andperspective view of the solid structure 230 only.

Similar to implant 210 ^(v), solid walls 237 of implant 210 ^(vi) extendbetween the solid support structure 230 proximate the upper and lowersurfaces 220, 222. The solid walls 237 support the cross struts 231 atlocations between the outer rim 232 and the inner rim 234 at the uppersurface 220 and at locations between the outer rim 236 and the inner rim238 at the lower surface 222. The solid walls 237 may extendcontinuously between the cross struts 231. As best seen in FIG. 192 ,the solid walls 237 may be recessed into, tied into, or positionedwithin a portion of the cross struts 231.

In this embodiment, the solid walls 237 may each include a straightsection and a curved section. The curved sections of the solid walls 237may be curved to mimic the nose of the implant 210 ^(vi) at the frontend 212. The solid walls 237 may be recessed a distance inward from theside walls 216, 218 such that the porous portions 250 cover the insideand outside surfaces of the solid walls 237. A portion of the side walls216, 218 may be the solid structure 230 and a portion may be the porousstructure 250 between the solid support structure 230. The interiorchamber 213 may be defined by both the solid structure 230 and theporous structure 250. The solid walls 237 may be sandwiched in betweenthe porous portions 250. The solid wall 237 may have a thickness lessthan a thickness of the porous portions 250.

The struts 231 or a portion thereof may form a plurality of teeth orserrations 224. These serrations 224 may be separate, discrete teeth.The upper and lower surfaces 220, 220 may also have a plurality of teethor serrations 226 near the rear end 214, which may be the same ordifferent than the teeth or serrations 224. A portion of the teeth 224,226 may also be chamfered to assist in rotation of the implant 210^(vi). As described in more detail U.S. Publication No. 2018/0200063,incorporated by reference herein in its entirety for all purposes,implant 210 ^(vi) may be an implant configured to inserted into a discspace at a lower height and then rotated 90° to a desired, final height.In other words, during insertion, the side walls 216, 218 are in contactwith the adjacent vertebrae, and then after rotation, the upper andlower surfaces 220, 222 are in contact with the adjacent vertebrae. Thisallows the implant to go into the disc space initially with its widthbeing considered its starting height. Once in the disc space, theimplant is rotatable to its final position, allowing for the desiredheight and lordosis.

Referring now to FIGS. 58-64 , one embodiment of a lateral lumbarinterbody fusion (LLIF) implant 310 will be described. As illustrated,the implant 310 has a body 311 with a generally rectangular shape. Thebody 311 is defined by a tapered front end 312, a rectangular rear end314 and side walls 316 and 318 extending therebetween. The implant 310has an outer perimeter OP extending about the body 311. A hollowinterior chamber 313 is defined within an inner perimeter IP of the body311. The hollow interior chamber 313 is configured to receive bonegrowth promoting materials. The implant 310 has an upper surface 320 anda substantially parallel lower surface 322, with both surfaces having atapering portion 323 at the front end 312. The upper and lower surfaces320, 322 define a plurality of serrations 324 along the side walls 316,318, a serration 328 along the front end 312 and a plurality ofserrations 326 along the rear end 314. The illustrated serrations 324,326, 328 have micro serrations defined thereon. The rear end 314 of theimplant 310 includes a hole 325 surrounded by a slot 327 for receivingan instrument that is used for inserting the implant 310. The implant310 is defined by a solid support structure 330 with an interfiled,integral porous structure 350.

Referring to FIGS. 62-64 , the solid support structure 330 includes anouter rim 332 extending about the outer perimeter OP of the uppersurface 320 and an inner rim 334 extending about the inner perimeter IPof the upper surface 320, i.e. about the interior chamber 313.Similarly, an outer rim 336 extends about the outer perimeter OP of thelower surface 322 and an inner rim 338 extends about the inner perimeterIP of the lower surface 322. A plurality of cross struts 331 extendbetween the outer rims 332, 336 and the respective inner rims 334, 338along the side wall areas. As seen in the figures, the cross struts 331along with contoured portions 333 of the rims 332, 334, 336, 338 definethe contour of the serrations 324. In addition to interconnecting therims within a given upper or lower surface, a plurality of X-shapedstruts 344 extend within each side wall area to interconnect the upperrims 332, 334 with the lower rims 336, 338.

A solid rear wall 335 additionally interconnects the outer rims 332, 336and the respective inner rims 334, 338 along the rear end area as wellas further connecting the upper and lower structures together. The solidrear wall 335 defines the hole 325 and slot 327. A portion of the rearwall 335 defining the hole 325 extends to a secondary rear wall 360which extends between the upper and lower inner rims 334, 338. A crossstrut 339 on the upper and lower sides of the rear wall 335 and aportion of the rear wall 335 define the serrations 326. A solid frontwall 340 also interconnects the outer rims 332, 336 and a secondaryfront wall 362 interconnects the inner rims 334, 338 along the front endarea. The front wall 340 includes an upper sloped portion 342 extendingbetween the upper outer rim 332 and inner rim 334 and a lower slopedportion 343 extending between the lower outer rim 336 and inner rim 338.While the rims and walls are described as specific elements for clarity,it is understood that the elements are formed as a unitary structure andmay be formed as a smooth structure without any distinction between theelements. A portion of the front wall 341 defines the serration 328.

In the illustrations of the support structure 330 in FIGS. 62-64 , it isseen that there is significant open space between the upper rims 332,334 and the lower rims 336, 338, between the inside surface of the frontwall 340 and the secondary wall 362 and on an inside surface of the rearwall 335. As illustrated in FIGS. 58-61 , in the implant 310, the openspaces are filled with the porous structure 350 such that itencapsulates the struts 344 and extends from the upper surface 320 tothe lower surface 322 and from the outer perimeter OP to the innerperimeter IP. In the illustrated embodiment, the porous structure 350substantially defines the inner perimeter IP and defines a substantialportion of the side walls 316, 318 along the outer perimeter OP.

Referring now to FIGS. 65-67 , an LLIF implant 310′ in accordance withanother embodiment of the disclosure will be described. The implant 310′is similar to the previous embodiment except for slight modification inthe structure of the support structure 330′ and a correspondingmodification in the porous structure 350′. Compared to the previousembodiment, the cross struts 331′ and 339′ do not includemini-serrations. Additionally, the rear wall 335′ has a narrower widthwith a portion of the rear end 314′ having an open support structureinto which the porous structure 350′ extends. The front end 312 of theimplant 310′ includes a cylindrical portion 364 extending between thefront wall 340 and the secondary front wall 362. Again, in the implant310′, the open spaces are filled with the porous structure 350′ suchthat the porous structure 350′ encapsulates the struts 344 and extendsfrom the upper surface 320 to the lower surface 322 and from the outerperimeter OP to the inner perimeter IP. In the illustrated embodiment,the porous structure 350′ substantially defines the inner perimeter IPand defines a substantial portion of the side walls 316′, 318′ along theouter perimeter OP.

Referring now to FIGS. 68 and 69 , an LLIF implant 310″ in accordancewith another embodiment of the disclosure will be described. The implant310″ is similar to the previous embodiment except for slightmodification in the structure of the support structure 330″ and acorresponding modification in the porous structure 350″. Compared to theprevious embodiment, the upper rims 332′, 334′ and lower rims 336′, 338′each have a wider configuration and do not have cross struts extendingtherebetween. The serrations 324′, 326′, 328′ are formed directly on therims 332′, 334′, 336′, 338′, on the rear wall 335′ and the front wall340′. Additionally, the struts 344 are interconnected to one another bya circumferential intermediate rim 365. Again, in the implant 310″, theopen spaces are filled with the porous structure 350″ such that theporous structure 350″ encapsulates the struts 344 and intermediate rim365 and extends from the upper surface 320 to the lower surface 322 andfrom the outer perimeter OP to the inner perimeter IP. In theillustrated embodiment, the porous structure 350″ substantially definesthe inner perimeter IP and defines a substantial portion of the sidewalls 316″, 318″ along the outer perimeter OP.

Referring now to FIGS. 70-72 , an LLIF implant 310′″ in accordance withanother embodiment of the disclosure will be described. The implant310′″ is similar to the embodiment illustrated in FIGS. 65-67 except forslight modification in the structure of the support structure 330′″ anda corresponding modification in the porous structure 350′″. Compared tothe embodiment illustrated in FIGS. 65-67 , the rims 332, 334, 336, 338do not have cross struts extending therebetween. Additionally, externalstruts 366 are provided along the outside perimeter OP along each sidewall 316′″, 318′″ and external struts 368 are provided along the insideperimeter IP along each side wall 316′″, 318′″. Again, in the implant310′″, the open spaces are filled with the porous structure 350′″ suchthat the porous structure 350′″ encapsulates the struts 344 and extendsfrom the upper surface 320 to the lower surface 322 and from the outerperimeter OP to the inner perimeter IP. The struts 366 are coplanar withthe porous structure 350′″ along the outer perimeter OP and the struts368 are coplanar with the porous structure 350′″ along the innerperimeter IP. In the illustrated embodiment, the porous structure 350′″substantially defines the inner perimeter IP and defines a substantialportion of the side walls 316′″, 318′″ along the outer perimeter OP.

Referring now to FIGS. 73-75 , an LLIF implant 310 ^(iv) in accordancewith another embodiment of the disclosure will be described. The implant310 ^(iv) is similar to the previous embodiment except for slightmodification in the structure of the support structure 330 ^(iv) and acorresponding modification in the porous structure 350 ^(iv). Comparedto the previous embodiment, the rims 332, 334, 336, 338 have crossstruts 331′ extending therebetween but do not include X-shaped strutswithin the side walls 316 ^(iv), 318 ^(iv). Again, in the implant 310^(iv), the open spaces are filled with the porous structure 350 ^(iv)such that the porous structure 350 ^(iv) extends from the upper surface320 to the lower surface 322 and from the outer perimeter OP to theinner perimeter IP. The struts 366 are coplanar with the porousstructure 350 ^(iv) along the outer perimeter OP and the struts 368 arecoplanar with the porous structure 350 ^(iv) along the inner perimeterIP. In the illustrated embodiment, the porous structure 350 ^(iv)substantially defines the inner perimeter IP and defines a substantialportion of the side walls 316 ^(iv), 318 ^(iv) along the outer perimeterOP.

Referring now to FIGS. 139-143 , an LLIF implant 310 ^(v) in accordancewith another embodiment of the disclosure will be described. The implant310 ^(v) is similar to the embodiment illustrated in FIGS. 58-64 exceptfor slight modification in the structure of the support structure 330^(v) and a corresponding modification in the porous structure 350 ^(v).In the present embodiment, the implant body 311′ has a wedgeconfiguration, tapering from a thickest height along the outer edge ofthe side wall 318 ^(v) to a thinnest height along the outer edge of theside wall 316 ^(v). The front wall 340″ and rear wall 335″ arecorrespondingly tapered. Additionally, the serration 328″ along thefront wall 340″ does not include micro serrations. As in the embodimentillustrated in FIGS. 58-64 , the rims 332, 334, 336, 338 have crossstruts 331 extending therebetween, but do not include X-shaped strutswithin the side walls 316 ^(v), 318 ^(v). Instead, each side wall 316^(v), 318 ^(v) has a single linear strut 369 extending perpendicularlybetween the upper outer rim 332 and the lower outer rim 336 at anapproximate mid-point of the side wall 316 ^(v), 318 ^(v). Again, in theimplant 310 ^(v), the open spaces are filled with the porous structure350 ^(v) such that the porous structure 350 ^(v) extends from the uppersurface 320 to the lower surface 322 and from the outer perimeter OP tothe inner perimeter IP. The struts 369 are coplanar with the porousstructure 350 ^(v) along the outer perimeter OP. In the illustratedembodiment, the porous structure 350 ^(v) substantially defines theinner perimeter IP and defines a substantial portion of the side walls316 ^(v), 318 ^(v) along the outer perimeter OP.

Referring now to FIGS. 144-147 , an LLIF implant 310 ^(vi) in accordancewith another embodiment of the disclosure will be described. The implant310 ^(vi) is similar to the embodiment illustrated in FIGS. 139-143except for slight modification in the structure of the support structure330 ^(v) and a corresponding modification in the porous structure 350^(vi). As in the previous embodiment, the implant body 311″ of thepresent embodiment has a wedge configuration, tapering from a thickestheight along the outer edge of the side wall 318 ^(vi) to a thinnestheight along the outer edge of the side wall 316 ^(v′). The front wall340′″ and rear wall 335′″ are correspondingly tapered. In the presentembodiment, the serrations 328″ along the front wall 340′″ and theserrations 326 along the rear wall 335′″ include micro serrations.

As in the previous embodiment illustrated, the rims 332, 334, 336, 338have cross struts 331 extending therebetween, but do not includeX-shaped struts within the side walls 316 ^(vi), 318 ^(vi). Furthermore,the side walls 316 ^(vi), 318 ^(vi) do not include the linear struts ofthe previous embodiment, but instead, the rims 332, 334, 336, 338 areonly interconnected at the front wall 340′″ and the rear wall 335′″. Asseen in the figures, contoured portions 333 extend forwardly andrearwardly from each of the cross struts 331 along the upper rims 332,334 and the lower rims 336, 338. The cross struts 331 along withcontoured portions 333 of the rims 332, 334, 336, 338 define the contourof the serrations 324′.

Again, in the implant 310 ^(vi), the open spaces are filled with theporous structure 350 ^(vi) such that the porous structure 350 ^(vi)extends from the upper surface 320 to the lower surface 322 and from theouter perimeter OP to the inner perimeter IP. In the illustratedembodiment, the porous structure 350 ^(vi) substantially defines theinner perimeter IP and defines a substantial portion of the side walls316 ^(vi), 318′ along the outer perimeter OP. The porous structure 350^(vi) also follows the contoured portions 333 in defining the shape ofeach of the serrations 324′.

Referring now to FIGS. 76-86 , embodiments of two-piece cervicalimplants 400, 400′ will be described. Each of the implants 400, 400′includes a plate 402, 402′ and connectable spacer 410. Each of theplates 402, 402′ defines bone screw holes 403 and one or more blockingset screws 404. The plates 402, 402′ may have varying configurationswith tabs 405 and projections 406. The plate configurations are notlimited to those shown. Each of the plates 402, 402′ includes arms 407with inward projections 408 which engage in slots 419 in the spacer 410to connect the spacer 410 with the respective plate 402, 402′. Theillustrated plates 402, 402′ are solid structures and do not includeporous structure, however, the plates may be made with portions having aporous structure.

Referring to FIGS. 80-86 , the spacer 410 has body 411 with a generallyU-shaped configuration. The body 411 is defined by a tapered front end412 with side walls 416 and 418 extending to free ends 414 a, 414 b. Thespacer 410 has an outer perimeter OP extending about the body 411 and aninner perimeter IP within the U-shape of the body 411. When the spacer410 is connected with a plate 402, 402′, a hollow interior chamber 413is defined which is configured to receive bone growth promotingmaterials. The spacer 410 has an upper surface 420 and a substantiallyparallel lower surface 422, with both surfaces having a tapering portion423 at the front end 412. The upper and lower surfaces 420, 422 define aplurality of serrations 424 along the side walls 416, 418, a serration428 along the front end 412 and serrations 426 at the free ends 414 a,414 b. Each side wall 416, 418 defines a connection slot 419 forward ofthe respective free end 414 a, 414 b. The slots 419 are engaged by theprojections 408 on the plate arms 407 to attach the spacer 410 to therespective plate 402, 402′. The spacer 410 is defined by a solid supportstructure 430 with an interfiled, integral porous structure 450.

Referring to FIGS. 84-86 , the solid support structure 430 includes anouter rim 432 extending about the outer perimeter OP of the uppersurface 420 and an inner rim 434 extending about the inner perimeter IPof the upper surface 420. Similarly, an outer rim 436 extends about theouter perimeter OP of the lower surface 422 and an inner rim 438 extendsabout the inner perimeter IP of the lower surface 422. A plurality ofcross struts 431 extend between the outer rims 432, 436 and therespective inner rims 434, 438 along the side wall areas. As seen in thefigures, the cross struts 431 along with contoured portions 433 of therims 432, 434, 436, 438 define the contour of the serrations 424.

A solid front wall 440 interconnects the outer rims 432, 436 along thefront end area. The front wall 440 includes an upper sloped portion 442and a lower sloped portion 443. While the rims and walls are describedas specific elements for clarity, it is understood that the elements areformed as a unitary structure and may be formed as a smooth structurewithout any distinction between the elements. A portion of the frontwall 440 defines the serration 428. A rear wall structure 435 a, 435 bat each free end 414 a, 414 b additionally interconnects the outer rims432, 436 and the respective inner rims 434, 438 along the rear end areaas well as further connecting the upper and lower structures together.The rear wall structure 435 a extends about an open area 460 with a sideopening 462 and rear wall structure 435 b extends about an open area 464with opposed side openings 465, 466.

In the illustrations of the support structure 430 in FIGS. 84-86 , it isseen that there is significant open space between the upper rims 432,434 and the lower rims 436, 438, between the inside surface of the frontwall 440 and the inner rims 434, 438 and within the open areas 460, 462.As illustrated in FIGS. 80-83 , in the spacer 410, the open spaces arefilled with the porous structure 450 such that it extends from the uppersurface 420 to the lower surface 422 and from the outer perimeter OP tothe inner perimeter IP. In the illustrated embodiment, the porousstructure 450 substantially defines the inner perimeter IP and defines asubstantial portion of the side walls 416, 418 along the outer perimeterOP.

Referring now to FIGS. 164-169 , a spacer 410′ in accordance withanother embodiment of the disclosure will be described. The spacer 410′is similar to the previous embodiment except for slight modification inthe structure of the support structure 430′ and a correspondingmodification in the porous structure 450′. In the present embodiment, alateral window 470 is defined through each of the side walls 416′, 418′.The lateral windows 470 may, for example, aid in assessing bony fusionin post-operative X-ray images. In the present embodiment, each lateralwindow 470 includes a respective solid window frame 471, however, it isunderstood that the lateral windows may be defined in the side walls416′, 418′ by the porous structure 450′ only without any solid frame orthe like.

In the present embodiment, each of the illustrative solid frames 471includes an outer frame ring 472. Each frame ring 472 has a widthapproximately equal to the width of the outer rims 432, 436, however,the width may be different therefrom. For example, the width may be suchthat the frame 471 extends from the outer perimeter OP to the innerperimeter IP. As another alternative, the solid frames 471 may includeinner and outer rings with cross struts extending therebetween. The rearends of the outer rings 472 each connect with the rear wall 435 tocantileverly support each of the solid frames 471.

As in the previous embodiments, all of the open spaces of the spacer410′ are filled with the porous structure 450′^(i) such that it extendsfrom the upper surface 420 to the lower surface 422. The porousstructure 450′^(i) will still substantially define the inner perimeterIP and will define a substantial portion of the side walls 416′^(v),418′, with the lateral windows 470 extending therethrough.

Referring now to FIGS. 89-96 , an embodiment of an articulating TLIFimplant 510 will be described. As illustrated, the implant 510 has abody 511 with a generally arcuate shape. The body 511 is defined by atapered front end 512, a rectangular rear end 514 and arcuate side walls516 and 518 extending therebetween. The implant 510 has an outerperimeter OP extending about the body 511. A hollow interior chamber 513is defined within an inner perimeter IP of the body 511. The hollowinterior chamber 513 is configured to receive bone growth promotingmaterials. The implant 510 has an upper surface 520 and a substantiallyparallel lower surface 522, with both surfaces having a tapering portion523 at the front end 512. The upper and lower surfaces 520, 522 define aplurality of serrations 524 along the side walls 516, 518 and aplurality of serrations 526 along the rear end 514. The rear end 514 ofthe implant 510 includes a hole 525 through one of the surfaces 522 anda slot 527 in communication therewith. An articulating member 570 ispositioned within the hole 525 and slot 527 and is pivotal relative tothe body 511. The articulating member 570 includes a body 572 receivedin and rotatable within the hole 525. A threaded tool receiving opening574 extends from the body 572 and is aligned within the slot 527. Athreaded implant tool is received in the threaded tool receiving opening574 and may be utilized for implanting and articulating the position ofthe implant 510 in a known manner. The articulating member 570 may bemanufactured during the 3D manufacturing process of the body 511 or maybe manufactured separately and thereafter positioned within the body511. The implant 510 is defined by a solid support structure 530 with aninterfiled, integral porous structure 550.

The solid support structure 530 includes an outer rim 532 extendingabout the outer perimeter OP of the upper surface 520 and an inner rim534 extending about the inner perimeter IP of the upper surface 520,i.e. about the interior chamber 513. Similarly, an outer rim 536 extendsabout the outer perimeter OP of the lower surface 522 and an inner rim538 extends about the inner perimeter IP of the lower surface 522. Aplurality of cross struts 531 extend between the outer rims 532, 536 andthe respective inner rims 534, 538 along the side wall areas. As seen inthe figures, the cross struts 531 along with contoured portions 533 ofthe rims 532, 534, 536, 538 define the contour of the serrations 524. Inaddition to interconnecting the rims within a given upper or lowersurface, external linear struts 560, 562 additionally interconnect therims 532, 534, 536, 538. An outer linear strut 560 extends along each ofthe side walls 516, 518 along the outer perimeter OP. The outer linearstruts 560 extend substantially perpendicular to the upper and lowerrims at an approximate midpoint of the respective wall. An inner linearstrut 562 extends along each of the side walls 516, 518 along the innerperimeter IP. The inner linear struts 562 extend substantiallyperpendicular to the upper and lower rims at an approximate midpoint ofthe respective wall.

The solid rear wall 535 additionally interconnects the outer rims 532,536 and the respective inner rims 534, 538 along the rear end area aswell as further connecting the upper and lower structures together. Thesolid rear wall 535 defines the hole 525 and slots 527. Recessed areas539 and 541 on the upper and lower sides of the rear wall 535 extendbetween the cross struts 537 and define the serrations 526, however, inthe present embodiment, these recesses generally do not receive porousstructure, as seen in FIGS. 89-92 . It is understood that these recessescould receive porous structure as in previous embodiments. The solidfront wall 540 also interconnects the outer rims 532, 536 and therespective inner rims 534, 538 along the front end area. The front wall540 includes an upper sloped portion 542 extending between the upperouter rim 532 and inner rim 534 and a lower sloped portion 543 extendingbetween the lower outer rim 536 and inner rim 538. While the rims andwalls are described as specific elements for clarity, it is understoodthat the elements are formed as a unitary structure and may be formed asa smooth structure without any distinction between the elements.

In the illustrations of the support structure 530 in FIGS. 93-96 , it isseen that there is significant open space between the upper rims 532,534 and the lower rims 536, 538 and between the inside surface of thefront wall 540 and the inner rims 534, 538. As illustrated in FIGS.89-92 , in the implant 510, the open spaces are filled with the porousstructure 550 such that it extends from the upper surface 520 to thelower surface 522 and from the outer perimeter OP to the inner perimeterIP. In the present embodiment, the struts 560, 562 are not encapsulatedin the porous structure 550, but instead the struts 560 are coplanarwith the porous structure 550 along the outer perimeter OP and thestruts 562 are coplanar with the porous structure 550 along the innerperimeter IP. Again, the porous structure 550 substantially defines theinner perimeter IP and defines a substantial portion of the side walls516, 518 along the outer perimeter OP.

Referring to FIGS. 97-99 , another embodiment of an intervertebralimplant 600 will be described. The implant 600 includes an upper plate602 and a lower plate 604 supported by a plurality of solid struts 606,608 extending therebetween. An open graft window 605 is defined withinthe implant 600. The struts 606, 608 are configured to provide desiredload bearing properties of the implant 600. The end plates 602, 604 maybe formed as a porous structure, for example, having a trabecularporosity. In addition to the porosity, the surfaces of the end plates602, 604 may have a nanoscale roughness formed thereon. As seen in FIG.98 , in the illustrated embodiment, the end plates 602, 604 and thestruts 606, 608 are configured such that the implant 600 has a biconvexsuperior and inferior geometry.

Referring to FIGS. 100 and 101 , another embodiment of an intervertebralimplant 610 will be described. The implant 610 includes an upper plate612 and a lower plate 614 supported by X-shaped struts 616 extendingbetween the plates 612, 614 on each lateral side of the implant 610. Anopen graft window 615 is defined within the implant 610 between theplates 612, 614. As shown in FIG. 101 , the window 615 may be configuredto receive an insertion tool 618. The end plates 602, 604 and struts 616may be formed as a porous structure. Alternatively, the struts 616 maybe formed as a solid structure. In addition to the porosity, thesurfaces of the end plates 612, 614 may have a roughness 613 formedthereon.

Referring to FIGS. 102-106 , another embodiment of an intervertebralimplant 620 will be described. The implant 620 includes an upper plate622 and a lower plate 624 supported by opposed solid walls 626, 628extending therebetween. Anterior and/or lateral windows 621 open into aninterior chamber 623 configured to receive graft material. Each of theupper and lower plates 622, 624 has a central open area 625 wherein aporous webbing surface 627 is formed. FIGS. 105 and 106 illustrateexamples of a porous webbing surface 627. The webbing may be formed witha grid or honeycomb pattern which is porous to bone ingrowth. Thewebbing may also be configured such that is may appear opaque whenturned past a critical angle. Such a feature may be used for assessingthe implants orientation or position.

Referring to FIGS. 107 and 108 , intervertebral implants 630, 640illustrating various features will be described. The implant 630 of FIG.107 includes a body 632 with an upper surface 634 and a lower surface636. One or both of the surfaces 634, 636 may be formed with a complexconfiguration to optimize end plate contact. For example, the uppersurface 634 has a biconcave configuration. Similarly, the implant 640 ofFIG. 108 includes a body 642 with an upper surface 644 and a lowersurface 646. One or both of the surfaces 644, 646 may be formed withvarious teeth or surface roughness features to minimize subsidence ormigration. For example, the upper surface 646 has a plurality of teeth648 defined thereon. For each of the implants 630, 640, the body 632,642 may include both solid structure and porous structure as describedherein.

Referring to FIG. 109 , another embodiment of an intervertebral implant650 will be described. The implant 650 includes an upper plate 652 and alower plate 654 supported by a plurality of solid struts 656 extendingtherebetween. The density of the struts 656 increases moving posteriorlyto provide a varying A-P stiffness to the implant, for example, tooptimize the load of an anterior graft.

Referring to FIGS. 110-113 , another embodiment of an intervertebralimplant 660 will be described. The implant 660 includes an upper surface662 and a lower surface 664 supported by a plurality of solid struts 666extending therebetween. The upper and lower surfaces 662, 664 aredefined by perimeter struts 667 and diagonal struts 668. As illustrated,the struts 666, 667, 668 that make up the support structure extendgenerally along the supporting edges while the remainder of the implantstructure remains open for either porous structure or ingrowth chambers.FIGS. 114 and 115 illustrate alternative strut configurations for eitherthe side walls or top or bottom surfaces of the implant 650. In theembodiment illustrated in FIG. 114 , the struts 666′, 668′ have arectangular central region with radial supports extending from thecorners thereof. In the embodiment illustrated in FIG. 115 , the struts666″, 668″ have a diamond shaped central region with octagon patternedstruts thereabout.

Referring to FIG. 116 , another embodiment of an intervertebral implant670 will be described. The implant 670 includes a body 671 with an uppersurface 672 and a lower surface 672 extending about an opening 613 intoan ingrowth cavity. The front end of the implant 670 includes slopedsurfaces 675 to define a smooth leading edge. One or both of thesurfaces 672, 672 may include a radial sawtooth configuration 676. As inprevious embodiments, the body 671 may include both solid structure andporous structure as described herein.

Referring to FIG. 117 , another embodiment of an intervertebral implant680 will be described. The implant 680 includes a solid support frame682 encased within porous structure 684, 686. The implant 680 defines atleast one opening 681 into an ingrowth chamber 683. In the illustratedembodiment, the porous structure includes areas of different densities.In the illustrated embodiment, the outer porous structure 684 has alower density than the inner porous structure 686. As described herein,the various implants may be formed with porous structures having varyingdensities, not just with respect to outer and inner layers, but alsowithin a given layer at different areas of the implant, e.g. anteriorversus posterior.

Referring to FIGS. 118 and 119 , another embodiment of an intervertebralimplant 690 will be described. The implant 690 includes a body 692extending about an ingrowth chamber 693. The body 692 is defined by aporous portion 696 surrounding a plurality of support struts 694. Thesupport struts 694 are not interconnected to one another. The supportstruts 694 may be a solid structure or may be a porous structure with agreater density than the porous portion 696. For example, the struts 694may be a porous structure having a cancellous density while the porousstructure 696 has a cortical density. Since the body 692 includes asignificant porous structure, the ingrowth chamber 693 may be smallerthan compared to an implant having a non-porous body.

Referring to FIGS. 120-122 , another embodiment of an intervertebralimplant 700 will be described. The implant 700 includes a body 702 withan ingrowth pocket 703 extending into the posterior side thereof. Thebody 702 is defined by a porous portion 706 surrounding a plurality ofsupport struts 704. The support struts 704 are not interconnected to oneanother. The support struts 704 may be a solid structure or may be aporous structure with a greater density than the porous portion 706. Forexample, the struts 704 may be a porous structure having a cancellousdensity while the porous structure 706 has a cortical density.

Referring to FIG. 123 , another embodiment of an intervertebral implant710 will be described. The implant 710 includes a body 712. The body 712is defined by an external area of higher density porous structure 714surrounding a less dense porous structure 716. The higher density porousstructure 714 acts as struts to provide the implant 710 strength. Thearea of higher density porous structure 714 is shown in a zig zagpattern, but may have other patterns and configurations.

Referring to FIGS. 124-126 , another embodiment of an intervertebralimplant 720 will be described. The implant 720 includes an upper plate722 and a lower plate 724. Each of the plates 722 and 724 has a waveconfiguration with minimum struts 726 interconnecting the plates 722,724. With such a configuration, the implant 720 has spring between theplates. An open graft window 723 is defined within the implant 720. Theplates 722, 724 and the struts 726 may include both solid structure andporous structure, as described herein.

Referring to FIGS. 127 and 128 , another embodiment of an intervertebralimplant 730 will be described. The implant 730 includes a body 732surrounding an ingrowth chamber 733. The body 732 is defined by a porousportion 734 which is surrounded a continuously wrapped support rib 736.The support rib 736 may be a solid structure or may be a porousstructure with a greater density than the porous portion 734.

Referring to FIG. 129 , another embodiment of an intervertebral implant740 will be described. The implant 740 includes interconnectable bodyportions 742 and 744. In the illustrated embodiment, the upper bodyportion 742 includes a post 743 configured to friction fit within a hole745 of the lower body portion 744. Various interconnectable upper andlower body portions 742, 744 may be printed and interconnected to form acustomized implant 740. In the illustrated embodiment, three additionallower body portions 744′, 744″, 744′″ and provided and all may beinterconnected with the upper body portion 742 to achieve implantshaving different configurations.

Referring to FIGS. 130-132 , another embodiment of an intervertebralimplant 750 and a method of implantation thereof will be described. Theimplant 750 includes a central body 752 and a pair of expandable wings753, 755. The implant 750 is connected to a hollow insertion tool 756and moved within an intervertebral space 759. Once in position, graftmaterial 757 is fed through the tool 756 and into the implant 750whereby the wings 753, 755 are caused to expand. Graft material 757 issupplied until the area within the central body 752 and the expandedwings 753, 755 is filled. The packed graft material 757 maintains theexpanded configuration of the implant 750.

Referring to FIGS. 133-135 , another embodiment of an intervertebralimplant 760 and a method of inserting such implant will be described.The implant 760 includes a body 762 extending about an ingrowth chamber763. The body 762 is generally defined by a porous structure 764. Solidbore holes 766 are defined within the body 762 and are configured toreceive screws or other anchors to facilitate fixation of the implant760. The body 762 also defines a tool receiving opening 765. In theillustrated embodiment, an expandable tool 770 is inserted through theopening 765. The expandable tool 770 includes a pair of legs 772 withflanges 773 on the end thereof. In a collapsed condition, the flanges773 pass through the opening 765. To engage the implant 760, a needle775 or the like is extended between the legs 772, thereby forcing theflanges 773 outward such that the engaged the inside surface of theimplant and do not pass through the opening 765 until the needle 775 isremoved.

Referring to FIGS. 136 and 137 , another tool and implant openinginterconnection assembly will be described. In the present embodiment,the implant 780 has a tool receiving opening 782 with a wider centralregion 783 and narrower end regions 784. The insertion tool 790 has ahead 792 with a complimentary configuration. The head 792 is positionedwithin the opening 782 with the orientation of the head 792 matchingthat of the opening 782 such that the head 792 passes through theopening 782. Once inside, the tool head 792 is rotated, for example, aquarter turn, such that the tool head 792 engages the inside surface ofthe implant 780 and is no longer removable through the opening 782. Asecuring sleeve 794 is threadably advanced along the tool 790 andengages the outside surface of the implant 780, securing the implant 780between the tool head 792 and the sleeve 794.

Referring to FIG. 138 , another tool and implant opening interconnectionassembly will be described. In the present embodiment, the implant 800has a tool receiving opening 802 with an outward taper 803 at the innerside of the opening 802. The insertion tool 810 has an outer hollow tube812 with a collet 814 on the free end thereof and an inner hollow tube816 with a through passage 817. The inner hollow tube 816 is axiallymoveable relative to the outer hollow tube 812. Initially, the innerhollow tube 816 is withdrawn into the outer hollow tube 812 such that itis clear of the collet 814 such that the collet 814 may collapse andpass through the implant opening 802. Once the collet 814 passes throughthe opening 802, the inner hollow tube 816 is moved forward such thatthe collet 814 is expanded outward and maintained in the outwardposition, engaging the tapered portion 803 of the implant opening 802.Graft material or the like may be passed into the implant 800 throughthe through passage 817.

Turning now to FIGS. 199-203 , a corpectomy implant 910 is provided. Thecorpectomy implant 910 may include one or more solid structures 930 andone or more porous structures 950. Corpectomy implant 910 may be similarto the expandable implants, for example, described in U.S. PublicationNos. 2016/0175106 and 2018/0021147, which are incorporated by referenceherein in their entireties for all purposes. The solid structure 930 ofthe implant 910 may include an inner member 912 which may betelescopingly received within an outer member 914. The implant 910further comprises a gear member 916 generally configured to effecttranslation of the inner member 912 with respect to the outer member 914thereby allowing for expansion and contraction of the implant 910. Theinner member 912, the outer member 914, and the gear member 916 may becentered along a longitudinal axis 918 and define a hollow interiorportion 920. At least a portion of this hollow interior portion 920 maybe filled with the porous structure 950. In one embodiment, the porousstructure 950 fills the entire interior portion 920 through the innermember 912, outer member 914, and the gear member 916. The porousstructure 950 may be any of the porous structures described herein.

The implant 910 may also include endplates 936, 940. Endplate 936connects to the inner member 912 and endplate 940 connects to the outermember 914. The endplates 936, 940 may also include hollow interiorportions 938, 942 which are in fluid communication with the hollowinterior portion 920 of inner member 912 and outer member 914,respectively. These interior portions 938, 942 may remain open, forexample to receive graft material, or optionally, at least a portion ofthe hollow interior portions 938, 942 may also be filled with porousstructure 950.

The porous structure 950 may promote bony in-growth, bone fusion and/orincrease stability of the implant 910. The porous structure 950 may havea porosity (open volume) of approximately 70%, and may featureinterconnected pores 300-800 um in diameter, for example. As describedherein, the porous structure may have a randomized pattern or arepeating pattern of pores. It is also envisioned that the porousstructure could be modeled from a bone source. For example, the porousstructure could be modeled by scanning a bone structure of a patient toprototype the 3D printed porous structure. The porous lattice structuremay help to promote fusion, for example, of the cervical and/orthoracolumbar spine by providing an osteoconductive structure thatbridges the endplates and graft material, when added.

As described herein, the implants of the disclosure generally comprise asolid or higher density support structure and a porous structure formedintegral therewith. The solid support structure may include solid frontand rear walls interconnected by upper and lower implant surfaces. Inseveral of the embodiments, the upper and lower surfaces include spacedapart rims with cross struts interconnecting the rims. In manyembodiments, the solid support structure of the upper and lower surfacesincludes a plurality of openings in which the integral porous structureis formed such that the porous structure extends along at least aportion of the upper and lower implant surfaces. The side wallsextending between the front and rear walls generally have a minimalsolid structure, for example, a plurality of struts extending betweenthe upper and lower rims, but otherwise have open area therebetween inwhich the integral porous structure is formed. The configuration of thesolid structure is selected to provide the implant sufficient structuralintegrity and mechanical stability while maximizing the area of porousstructure which facilitates better integration/incorporation with theadjacent bone. In several embodiments of the disclosure, the solidstructure generally encases the corners of the porous structure orotherwise houses the porous structure therein to maintain the structuralintegrity of the porous structure.

Although the invention has been described in detail and with referenceto specific embodiments, it will be apparent to one skilled in the artthat various changes and modifications can be made without departingfrom the spirit and scope of the invention. Thus, it is intended thatthe invention covers the modifications and variations of this inventionprovided they come within the scope of the appended claims and theirequivalents. It is expressly intended, for example, that all rangesbroadly recited in this document include within their scope all narrowerranges which fall within the broader ranges. It is also intended thatthe components of the various devices disclosed above may be combined ormodified in any suitable configuration.

What is claimed is:
 1. A corpectomy implant comprising: an innercylindrical member defining a hollow inner chamber and having a firstend plate adapted to engage a surface of a first vertebral body; anouter cylindrical member defining a hollow inner chamber and having asecond end plate adapted to engage a surface of a second vertebral body,the outer cylinder telescopingly receiving the inner member; a porousstructure disposed in the inner chamber of the inner cylindrical memberfor encouraging bone growth, wherein the inner cylindrical member andthe porous structure are 3D printed structures containing the same 3Dprinting material and the porous structure is formed integrally with theinner cylindrical member.
 2. The corpectomy implant of claim 1, whereinthe porous structure is a 3D printed porous lattice structure.
 3. Thecorpectomy implant of claim 1, wherein the porous structure is a 3Dprinted porous structure, which has been modeled after the bonestructure of the patient.
 4. The corpectomy implant of claim 1, whereinthe porous structure has interconnected pores that are in the range of300-800 um in diameter.
 5. The corpectomy implant of claim 1, whereinthe porous structure porosity is approximately 70%.
 6. The corpectomyimplant of claim 1, wherein the porous structure has interconnectedpores that are in the range of 300-800 um in diameter and the pores havea randomized pattern.
 7. The corpectomy implant of claim 1, wherein atleast one of the first and second end plates have an opening throughwhich graft material is received.
 8. The corpectomy implant of claim 1,wherein the inner member includes outer threads that engage with innerthreads of a gear.
 9. The corpectomy implant of claim 8, wherein: theinner member includes outer threads that engage with inner threads ofthe gear; and the gear is positioned between an outer wall of the innercylindrical member and an inner wall of the outer cylindrical member.10. A corpectomy implant comprising: an inner cylindrical memberdefining a hollow inner chamber and having a first end plate adapted toengage a surface of a first vertebral body, the inner cylindrical memberhaving an outer threading; an outer cylindrical member defining a hollowinner chamber and having a second end plate adapted to engage a surfaceof a second vertebral body, the outer cylinder telescopingly receivingthe inner member, the inner and outer cylindrical members adapted to bepositioned in a space occupied by a removed vertebral body; a 3D printedporous structure disposed in the inner chamber of the inner cylindricalmember, wherein the inner cylindrical member and the porous structurescontain the same 3D printing material and the porous structure is formedand 3D printed integrally with the inner cylindrical member.
 11. Thecorpectomy implant of claim 11, wherein the porous structure is acustomized 3D printed porous structure, which has been modeled after thebone structure of the patient.
 12. The corpectomy implant of claim 11,wherein the porous structure has interconnected pores that are in therange of 300-800 um in diameter.
 13. The corpectomy implant of claim 11,wherein at least one of the first and second end plates have an openingthrough which graft material is received.
 14. The corpectomy implant ofclaim 11, wherein the porous structure has interconnected pores that arein the range of 300-800 um in diameter and the pores have a repeatingpattern.
 15. The corpectomy implant of claim 11, wherein the 3D printedporous structure is a porous lattice structure having interconnectedpores that are in the range of 300-800 um in diameter.